July 4, 2022
sysbio

dimensional proteomic evaluation of serum exhibits immunological proteins completely expressed in sulfur mustard uncovered sufferers

Blood-Mind Barrier Protein Claudin-5 Expressed in Paired Xenopus laevis Oocytes Mediates Cell-Cell Interplay

Claudin-5 determines the sealing properties of blood-brain barrier tight junctions and its perform is impaired in neurodegenerative and neuroinflammatory problems. Specializing in the contribution of claudin-5 to the trans-interaction throughout the tight junction seal, we used Xenopus laevis oocytes as an expression system. Cells had been clustered and challenged in a novel strategy for the evaluation of claudin interplay. We evaluated the strengthening impact of claudin-5 to cell-cell-connection compared to claudin-3.

Utility of a hydrostatic stress impulse on clustered management oocyte pairs revealed a discount of contact areas. In distinction, mixtures with each oocytes expressing claudins maintained an enhanced connection between the cells (cldn5-cldn5, cldn3-cldn3). Energy of interplay was elevated by each claudin-Three and claudin-5.

This novel strategy allowed an evaluation of single claudins contributing to tight junction integrity, characterizing homophilic and hetrophilic trans-interaction of claudins. To check a brand new screening strategy for barrier effectors, exemplarily, this 2-cell mannequin of oocytes was used to investigate the impact of the absorption enhancer sodium caprate on the oocyte pairs.

Two dimensional proteomic evaluation of serum exhibits immunological proteins completely expressed in sulfur mustard uncovered sufferers with long run pulmonary problems

Background: Regardless of greater than 30 years after utilization of sulfur mustard or bis (2-chloroethyl) sulfide (SM) by Iraqi troops towards Iranian army members and civilians, there are a whole lot of reported delayed problems for the uncovered folks. Nonetheless, the molecular mechanism of motion from this chemical warfare agent just isn’t acknowledged but.

Materials and technique: On this examine, we employed two dimensional gel electrophoresis (2DE) method to analyze the serum proteins from chemical uncovered folks in comparison with non-exposed people to offer an inside into molecular mechanism of this chemical agent. Every group was divided into two subgroups together with people with, and with out respiratory problems. For every group, 10 people had been included after knowledgeable consent.

End result: The outcomes confirmed protein spots, which had been completely/primarily expressed in chemical uncovered sufferers with problems, together with T cell receptor alpha, and hematopoietic cell sign transducer. Additionally there have been protein spots that had been expressed solely in all uncovered teams (with and with out problems). Alternatively, we might determine protein spots that had been completely expressed/altered solely in non-exposed group with problems together with Pre T-cell antigen receptor, CD40 ligand, and multidrug and toxin extrusion proteins.

Conclusion: Our investigation might lead to identification of proteins which are related to chemical publicity, in addition to these particular for respiratory problems no matter chemical publicity. These candidate proteins can be utilized as biomarker, in addition to a base for understanding the molecular mechanism of this chemical agent.

sysbio
sysbio

Anti-CD163

DB-045-0.5 500 μl
EUR 384
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-CD163

DB-045-1 1 ml
EUR 613
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-CD163

DB-045-RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD163

DB-045-RTU-7 7 ml
EUR 231
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD163

DB045RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD163

DB045RTU-7 7 ml
EUR 231
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Mouse Cluster Of Differentiation (CD163) ELISA Kit

DLR-CD163-Mu-48T 48T
EUR 508
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Cluster Of Differentiation (CD163) in samples from serum, plasma or other biological fluids.

Mouse Cluster Of Differentiation (CD163) ELISA Kit

DLR-CD163-Mu-96T 96T
EUR 661
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Cluster Of Differentiation (CD163) in samples from serum, plasma or other biological fluids.

Rat Cluster Of Differentiation (CD163) ELISA Kit

DLR-CD163-Ra-48T 48T
EUR 508
Description: A sandwich quantitative ELISA assay kit for detection of Rat Cluster Of Differentiation (CD163) in samples from serum, plasma, tissue homogenates or other biological fluids.

Rat Cluster Of Differentiation (CD163) ELISA Kit

DLR-CD163-Ra-96T 96T
EUR 661
Description: A sandwich quantitative ELISA assay kit for detection of Rat Cluster Of Differentiation (CD163) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse Cluster Of Differentiation (CD163) ELISA Kit

RD-CD163-Mu-48Tests 48 Tests
EUR 511

Mouse Cluster Of Differentiation (CD163) ELISA Kit

RD-CD163-Mu-96Tests 96 Tests
EUR 709

Rat Cluster Of Differentiation (CD163) ELISA Kit

RD-CD163-Ra-48Tests 48 Tests
EUR 511

Rat Cluster Of Differentiation (CD163) ELISA Kit

RD-CD163-Ra-96Tests 96 Tests
EUR 709

Mouse Cluster Of Differentiation (CD163) ELISA Kit

RDR-CD163-Mu-48Tests 48 Tests
EUR 534

Mouse Cluster Of Differentiation (CD163) ELISA Kit

RDR-CD163-Mu-96Tests 96 Tests
EUR 742

Rat Cluster Of Differentiation (CD163) ELISA Kit

RDR-CD163-Ra-48Tests 48 Tests
EUR 534

Rat Cluster Of Differentiation (CD163) ELISA Kit

RDR-CD163-Ra-96Tests 96 Tests
EUR 742

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

Anti-CD163 Antibody

PA1874 100ug/vial
EUR 294

Anti-CD163 Antibody

PA1874-1 100ug/vial
EUR 334

Anti-CD163 Antibody

A00812-1 100ug/vial
EUR 334

Anti-CD163 antibody

STJ110681 100 µl
EUR 277
Description: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Anti-CD163 antibody

STJ160082 1 mL C
EUR 941

Anti-CD163 antibody

STJ16100302 100 µg
EUR 720

Anti-CD163 antibody

STJ16100324 1 mL
EUR 979

Anti-CD163 antibody

STJ180301 0.1 ml
EUR 215

Anti-CD163 Antibody

STJ500423 100 µg
EUR 476

Anti-CD163 Antibody

STJ500424 100 µg
EUR 476

Anti-CD163 antibody

STJ190009 200 µl
EUR 197
Description: Unconjugated Mouse monoclonal to CD163 (AS1A1)

Anti-CD163/M130 antibody

PAab09771 100 ug
EUR 355

Anti-Hu CD163 APC

1A-645-T025 25 tests
EUR 140

Anti-Hu CD163 APC

1A-645-T100 100 tests
EUR 240

Anti-Hu CD163 PE

1P-645-T025 25 tests
EUR 140

Anti-Hu CD163 PE

1P-645-T100 100 tests
EUR 240

Anti-CD163/M130 Antibody

A00812 100ul
EUR 397
Description: Rabbit IgG polyclonal antibody for Scavenger receptor cysteine-rich type 1 protein M130 (CD163) detection.tested for IF, IHC, WB in Human, Mouse, Rat. Various direct flourescent conjugates are available for FCM upon request. Please contact us for details.

Anti-Hu CD163 Purified

11-645-C025 0.025 mg
EUR 99

Anti-Hu CD163 Purified

11-645-C100 0.1 mg
EUR 158

Anti-CD163 Antibody BIOTIN

STJ500425 100 µg
EUR 586

Anti-CD163 Antibody FITC

STJ500426 100 µg
EUR 586

Anti-CD163 Antibody BIOTIN

STJ500427 100 µg
EUR 586

Anti-CD163 Antibody FITC

STJ500428 100 µg
EUR 586

anti- CD163/M130 Antibody

FNab09771 100µg
EUR 548.75
Description: Antibody raised against CD163/M130 

Human CD163 antigen(CD163)ISA kit

GA-E0263HM-48T 48T
EUR 289

Human CD163 antigen(CD163)ISA kit

GA-E0263HM-96T 96T
EUR 466

human CD163 antigen,CD163 LISA kit

201-12-0247 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human CD163 antigen(CD163)ISA kit

QY-E05066 96T
EUR 361

Mouse Anti Human Cd163 Monoclonal Antibody

CABT-47162MH 25 µg
EUR 372

Mouse Anti Human Cd163 Monoclonal Antibody

CABT-47163MH 0.2 mg
EUR 881

Anti-CD163 Rabbit Monoclonal Antibody

M00812 100ug/vial
EUR 397
Description: Rabbit Monoclonal CD163 Antibody. Validated in IP, WB and tested in Human.

Anti-Hu CD163 PE-Cy7

T7-645-T025 25 tests
EUR 154

Anti-Hu CD163 PE-Cy7

T7-645-T100 100 tests
EUR 268

Anti-Hu CD163 PerCP-Cy5.5

T9-645-T025 25 tests
EUR 196

Anti-Hu CD163 PerCP-Cy5.5

T9-645-T100 100 tests
EUR 352

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Porcine CD163 antigen,CD163 LISA kit

GA-E0045PC-48T 48T
EUR 364

Porcine CD163 antigen,CD163 LISA kit

GA-E0045PC-96T 96T
EUR 590

Canine CD163 antigen(CD163 LISA kit

GA-E0062CN-48T 48T
EUR 402

Canine CD163 antigen(CD163 LISA kit

GA-E0062CN-96T 96T
EUR 684

CD163 Antibody

ABD8235 100 ug
EUR 438

CD163 antibody

10R-CD163aRT 250 ug
EUR 716
Description: Mouse monoclonal CD163 antibody

CD163 antibody

10R-6496 100 ug
EUR 203
Description: Mouse monoclonal CD163 antibody

CD163 Antibody

DF8235 200ul
EUR 304
Description: CD163 Antibody detects endogenous levels of total CD163.

Cd163 Antibody

1-CSB-PA650452LA01MO
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Cd163. Recognizes Cd163 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:500-1:2000

CD163 Antibody

1-CSB-PA969205
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100

CD163 Antibody

1-CSB-PA801238LA01HU
  • EUR 317.00
  • EUR 335.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF; Recommended dilution: IF:1:50-1:200

CD163 Antibody

20-abx242956
  • EUR 467.00
  • EUR 328.00
  • 100 ul
  • 50 ul

CD163 Antibody

37157-100ul 100ul
EUR 252

CD163 siRNA

20-abx910930
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

CD163 siRNA

20-abx910931
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

CD163 Antibody

49553-100ul 100ul
EUR 333

CD163 Antibody

49553-50ul 50ul
EUR 239

Mouse Anti Rat Cd163 Monoclonal Antibody

DMABT-47170MR 0.25 mg
EUR 741

Mouse Anti Rat Cd163 Monoclonal Antibody

DMABT-47171MR 0.1 mg
EUR 559

Human CD163 ELISA Kit

ELA-E1726h 96 Tests
EUR 824

Human CD163 ELISA Kit

LF-EK50890 1×96T
EUR 648

Human CD163 shRNA Plasmid

20-abx956176
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Mouse Anti-Human CD163 monoclonal antibody, clone JID274

CABT-L2938-100uL500uL 100 uL, 500 uL
EUR 502

Anti-Human CD163 DyLight® 488 conjugated Antibody

A00812-Dyl488 100ug/vial
EUR 344

Anti-Human CD163 DyLight® 550 conjugated Antibody

A00812-Dyl550 100ug/vial
EUR 344

Human CellExp? CD163, Human recombinant

9226-10
EUR 305

Human CellExp? CD163, Human recombinant

9226-50
EUR 773

Anti-CD163 Rabbit Monoclonal Antibody, Clone#RM371

M00812-1 100uL
EUR 385
Description: Anti-CD163 Rabbit Monoclonal Antibody, Clone#RM371 tested in WB, IHC, reactive to Human

Mouse Anti Rat Cd163 Monoclonal Antibody,Biotin

DMABT-47168MR 0.1 mg
EUR 881

Mouse Anti Rat Cd163 Monoclonal Antibody,FITC

DMABT-47169MR 0.1 mg
EUR 881

Mouse Anti Rat Cd163 Monoclonal Antibody,RPE

DMABT-47172MR 100 TEST
EUR 892

Mouse Anti Pig Cd163 Monoclonal Antibody,FITC

CABT-47164MP 0.1 mg
EUR 881

Mouse Anti Pig Cd163 Monoclonal Antibody,RPE

CABT-47166MP 100 TEST
EUR 715

CD163 antibody (PE)

61R-1319 100 tests
EUR 403
Description: Mouse monoclonal CD163 antibody (PE)

CD163 antibody (biotin)

61R-1569 100 ug
EUR 349
Description: Mouse monoclonal CD163 antibody (biotin)

Quantitative evaluation of differentially expressed proteins in psoriasis vulgaris utilizing tandem mass tags and parallel response monitoring

Background: Psoriasis vulgaris (PV) is a continual autoimmune inflammatory illness with epidermal hyperkeratosis and parakeratosis.

Strategies: The examine was to elucidate the pathogenesis of PV by quantitative proteomic evaluation of pores and skin lesion biopsies of PV and wholesome tissues with tandem mass tags (TMTs) coupled with liquid chromatography-mass spectrometry (LC-MS)/MS.

Outcomes: A complete of 4562 differentially expressed proteins (DEPs) between PV lesional tissues (n = 11) and wholesome tissues (n = 11) had been recognized, of which 299 had been upregulated and 206 had been downregulated utilizing |fold change| > 1.Three because the cutoff threshold.

The Gene Ontology (GO) annotation and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment evaluation revealed that the DEPs had been primarily enriched within the activation of immune cells (drug metabolism pathway, NOD-like pathway, and IL-17 pathway), cell proliferation (ribosomal pathway, DNA replication pathway, and base replication pathway), metabolism-related pathways (fatty acid biosynthesis and metabolism, PPAR pathway, glycerophospholipid metabolism, and cortisol synthesis and breakdown), and glandular secretion (saliva secretion, gastric acid secretion, and pancreatic fluid secretion).

13 DEPs that had been comparatively extremely expressed within the drug metabolism pathway had been validated with parallel response monitoring (PRM), of which MPO, TYMP, IMPDH2, GSTM4, and ALDH3A1 had been extremely expressed in PV, whereas CES1, MAOB, MGST1, and GSTT1 had been much less expressed in PV.

Conclusions: These findings confirmed that these proteins take part within the drug metabolism-other enzyme pathways and play essential roles within the activation and proliferation of immune cells within the pathogenesis of PV.

IL-1 R2 ELISA Kit (Human) : 96 Wells (OKAG00129)

OKAG00129 96 Wells
EUR 596
Description: Description of target: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.;Species reactivity: Human;Application: ELISA;Assay info: Quantitative Colorimentric Sandwich ELISA;Sensitivity: 32 pg/mL

anti-PKA R2

YF-PA13990 50 ul
EUR 363
Description: Mouse polyclonal to PKA R2

anti-PKA R2

YF-PA24454 50 ul
EUR 334
Description: Mouse polyclonal to PKA R2

Anti-IL1R2/Il 1 Rii Antibody

A03106-1 1 ml
EUR 397
Description: Rabbit Polyclonal IL1R2/Il 1 Rii Antibody. Validated in IP, WB and tested in Human.

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

Anti-IL-6 Antibody

A00102-1 100ug
EUR 432
Description: Rabbit Polyclonal IL-6 Antibody. Validated in Neu, IHC, WB and tested in Human.

Anti-IL-31 Antibody

A08339-1 100ug/vial
EUR 334

Anti-IL-17B Antibody

A10846-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for IL-17B Antibody (IL17B) detection.tested for IHC in Human, Rat.

Anti-PKA R2 (6A9)

YF-MA10721 100 ug
EUR 363
Description: Mouse monoclonal to PKA R2

Anti-PKA R2 (3C7)

YF-MA14876 100 ug
EUR 363
Description: Mouse monoclonal to PKA R2

Anti-MonoMethylH3R2me1-(R2) antibody

STJ24010 100 µl
EUR 393
Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Anti-GABAB R2 antibody

STJ96379 200 µl
EUR 197
Description: Rabbit polyclonal to GABAB R2.

Anti-TNF-R2 antibody

STJ96053 200 µl
EUR 197
Description: Rabbit polyclonal to TNF-R2.

Anti-IL-2/IL2 Antibody

A00387-1 100ug/vial
EUR 294

Anti-IL-8 Monoclonal Antibody

A00423-1 100ul
EUR 397
Description: Mouse Monoclonal Antibody for IL-8 Antibody (CXCL8) detection. Tested with IHC in Human, Mouse, Rat.

Anti-IL-22/IL22 Antibody

A00963-1 100ug/vial
EUR 294

Anti-IL-3R beta Antibody

A02219-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for IL-3R beta Antibody (CSF2RB) detection.tested for WB in Human, Mouse, Rat.

Anti-IL-6 Monoclonal Antibody

M00102-1 100ug
EUR 455
Description: Mouse Monoclonal IL-6 Antibody. Validated in Flow Cytometry, WB and tested in Human.

Anti-IL-17A Monoclonal Antibody

M00421-1 100ug
EUR 455
Description: Mouse Monoclonal IL-17A Antibody. Validated in WB and tested in Human.

Rat Anti-Mouse IL-12 p75 Monoclonal antibody, clone R2-9A5

CABT-L4486-1mg 1 mg
EUR 897

Rat Anti-Mouse IL-12 p75 Monoclonal antibody, clone R2-9A5

CABT-L4486-5mg 5 mg
EUR 2405

IL-1 β

E13-003-1 10μg
EUR 213

IL-1 α

E13-029-1 10μg
EUR 213

Anti-Human IL-17F Biotin Conjugated Monoclonal Antibody

B02062-1 100ug
EUR 432
Description: Mouse Monoclonal Human IL-17F Biotin Conjugated Antibody. Validated in IHC, WB and tested in Human.

Anti-GABA(B) R2 Purified

11-551-C100 0.1 mg
EUR 204

Anti-IL-32A Antibody Peroxidase Conjugated

A03286-1 100ug
EUR 455
Description: Rabbit Polyclonal IL-32A Antibody Peroxidase Conjugated. Validated in WB and tested in Human.

IL-1 beta, rat recombinant

P1019-1 1 mg
EUR 7288
Description: Interleukin 1 beta (IL-1?) is a proinflammatory cytokine and is produced by activated macrophages, monocytes, keratinocytes and other epithelial cells. Both IL-1? and IL-1? bind to the same receptor and have similar biological properties.

Notoginsenoside R2

TN028181 20mg Ask for price

Stipuleanoside R2

TBZ1475 unit Ask for price

Notoginsenoside R2

HY-N0909 10mg
EUR 463

IL-1beta, human recombinant

P1018-1 1 mg
EUR 5061
Description: Interleukin 1 beta (IL-1?) is a proinflammatory cytokine and is produced by activated macrophages, monocytes, keratinocytes and other epithelial cells

IL-2, human recombinant

P1020-1 1 mg
EUR 1156
Description: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes and is produced by activated CD4+ and CD8+ T cells, gamma ? T cells, B cells, dendritic cells and eosinophils. IL-2 plays a critical role in immune responses against pathogenic infection

IL-3, human recombinant

P1021-1 1 mg
EUR 4017
Description: Interleukin 3 (IL-3) is a pleiotropic cytokine produced by activated T cells, mast cells and eosinophils, and stimulates the proliferation and differentiation of pluripotent hematopoietic stem cells, and committed progenitor cells of the megakaryocyte

IL-7, human recombinant

P1024-1 1 mg
EUR 6940
Description: Interleukin-7 (IL-7) is a potent lymphoid cell growth factor produced by bone marrow and thymic stromal cells, spleen cells and keratinocytes. IL7 stimulates the proliferation of Pre-B, Pro-B and early T cells.

Human Interleukin-1 beta (IL-1 beta) AssayMax ELISA Kit

EI2200-1 96 Well Plate
EUR 477

Human Interleukin-1-alpha (IL-1-alpha) AssayMax ELISA Kit

EI2301-1 96 Well Plate
EUR 477

Recombinant Rat IL-1 Beta Protein

PROTQ63264-1 10ug
EUR 317
Description: IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant rat IL-1β is a 17.4 kDa protein containing 153 amino acid residues.

Canine IL-1 beta Recombinant Protein

R00101-1 5ug/vial
EUR 259
Description: IL-1 beta (IL-1β) is a member of the interleukin 1 family of cytokines. The IL-1 beta cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Canine IL-1 beta Recombinant Protein is purified interleukin-1 beta cytokine produced in yeast.

Canine IL-1 alpha Recombinant Protein

R01144-1 5ug/vial
EUR 259
Description: IL-1 alpha (IL-1α, IL-1F1) is a member of the interleukin 1 family of cytokines. IL-1 alpha is an inflammatory cytokine active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. Canine IL-1 alpha Recombinant Protein is purified interleukin-1 alpha cytokine produced in yeast.

Anti-Phospho-GABAB R2 (Ser783) Antibody

P03830 100ul
EUR 398
Description: Rabbit Polyclonal Phospho-GABAB R2 (Ser783) Antibody. Validated in IF, WB and tested in Mouse, Rat.

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

IL-1-alpha Interleukin-1 alpha Human Recombinant Protein, His Tag

PROTP01583-1 Regular: 20ug
EUR 317
Description: IL-1A Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 159 amino acids fragment (113-271) with an amino-terminal hexahistidine tag and having a total molecular mass of 22.5kDa. ;The Interleukin-1 alpha His-tag is purified by proprietary chromatographic techniques.

IL-1-beta Interleukin-1 betaHuman Recombinant Protein

PROTP01584-1 Regular: 10ug
EUR 317
Description: Interleukin-1 beta Human Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 153 amino acids and having a molecular mass of 17000 Dalton.;The IL-1b is purified by proprietary chromatographic techniques.

Recombinant Human IL-24 Protein

PROTQ13007-1 20ug
EUR 317
Description: IL-24 is a secreted glycoprotein belonging to the IL-10 structural family of cytokines. It is produced by a variety of cell types, including B cells, CD4+ cells, NK cells, lymph node DCs, monocytes, and melanoma cells. IL-24 can signal through the IL20R1/IL20R2 and IL22R1/IL20R2 receptors to initiate a signaling cascade which includes the induction of JAK1/STAT3 phosphorylation. IL-24 is, functionally, a pleiotropic protein but is generally characterized as an anti-cancer cytokine that can selectively inhibit growth of a wide variety of human cancer cells through activities that include the induction of differentiation and apoptosis, and the suppression of angiogenesis and cell proliferation. Recombinant human IL-24 is an 18.9 kDa glycoprotein, containing 161 amino acid residues, including a C-terminal His-tag.

Recombinant Human IL-31 Protein

PROTQ6EBC2-1 10ug
EUR 317
Description: Human IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant IL-31 is a 15.8 kDa protein containing 141 amino acid residues.

Recombinant Human IL-17D Protein

PROTQ8TAD2-1 25ug
EUR 317
Description: IL-17D is a disulfide-linked homodimer of two 185 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17D has the ability to stimulate the production of IL-6, IL-8, and GM-CSF and inhibits hemopoiesis of myeloid progenitor cells in colony forming assays. Recombinant human IL-17D is a 40.5 kDa disulfide-linked homodimer of two 185 amino acid polypeptide chains.

Recombinant Human IL-22 Protein

PROTQ9GZX6-1 10ug
EUR 317
Description: IL-22 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10R-β/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family. Recombinant human IL-22 is a 33.6 kDa non-disulfide-linked homodimeric protein containing of two 146 amino acid polypeptide chains.

Recombinant Human IL-17E Protein

PROTQ9H293-1 25ug
EUR 317
Description: IL-17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulated secretion of IL-8, and induces activation of the transcription factor NF-κB in cells that express the IL-17BR receptor. Recombinant human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 145 amino acid polypeptide chains.

Recombinant Human IL-20 Protein

PROTQ9NYY1-1 10ug
EUR 317
Description: IL-20 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. IL-20 signals through a receptor system composed of type I IL-20R-α and type II IL-20R-β. Over-expression of IL-20 in keratinocytes expressing both receptor subunits has been implicated in the induction of inflammatory skin disease. Recombinant human IL-20 is a 35.2 kDa homodimeric protein consisting of two 153 amino acid polypeptide chains.

Recombinant Human IL-19 Protein

PROTQ9UHD0-1 10ug
EUR 317
Description: IL-19 belongs to the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. Preliminary data suggests that IL-19 is a proinflammatory cytokine because it up-regulates IL-6 and TNF-α and induces apoptosis through TNF-α. IL-19 signals through the type I IL-20R. Human and murine IL-19 share 71% amino acid sequence identity. Recombinant human IL-19 is a 17.9 kDa protein containing 153 amino acid residues. In solution IL-19 exists predominantly as a non-disulfide-linked dimer.

Recombinant Human IL-12 Protein

PROTP29459-1 10ug
EUR 317
Description: IL-12 is a potent regulator of cell mediated immune responses and it induces IFN-γ production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue type mast cells. Among its biological activities IL-12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells and induces the development of IFN-γ producing Th1 cells. Recombinant Human IL-12 is a 75.0 kDa heterodimeric glycoprotein consisting of disulfide-linked 35 kDa (p35) and 40 kDa (p40) subunits (503 total amino acid residues).

IL-10, human recombinant protein

P1028-1 1 mg
EUR 6731
Description: Interleukin-10 (IL-10) is an immunosuppressive cytokine produced by macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the synthesis of proinflammatory cytokines such as IL-1 and TNF-? and proliferation of T cells

IL-15, human recombinant protein

P1029-1 1 mg
EUR 5339
Description: Interleukin 15 (IL-15) is an immunomodulating cytokine mainly produced by adherent peripheral blood mononuclear cells, fibroblasts and epithelial cells and stimulates the proliferation of T lymphocytes.

IL-17A, human recombinant protein

P1030-1 1 mg
EUR 4156
Description: Interleukin-17A (IL-17A) is a proinflammatory cytokine produced by Th17 cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases and stimulates the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as the production of nitric oxide (NO).

IL-18, human recombinant protein

P1032-.1 100 µg
EUR 780
Description: Interleukin-18 (IL-18) is a proinflammatory cytokine produced by monocyte/macrophages, osteoblasts and keratinocytes, as a proprotein which is proteolytically processed to its active form by caspase-1. Human IL-18 can enhance NK cell activity in PBMC cultures.

IL-18, human recombinant protein

P1032-1 1 mg
EUR 5061
Description: Interleukin-18 (IL-18) is a proinflammatory cytokine produced by monocyte/macrophages, osteoblasts and keratinocytes, as a proprotein which is proteolytically processed to its active form by caspase-1. Human IL-18 can enhance NK cell activity in PBMC cultures.

IL-21, human recombinant protein

P1033-1 1 mg
EUR 6522
Description: Interleukin-21 (IL-21) is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. IL-21 induces the differentiation of T-cell-stimulated B-cells into plasma cells and memory B-cells, apoptotic effects in naïve B-cells.

Recombinant Murine IL-17 (IL-17A) Protein

PROTQ62386-1 25ug
EUR 317
Description: The originally described IL-17 protein, now known as IL-17A, is a disulfide linked homodimer, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells. Recombinant murine IL-17A is a 30.0 kDa disulfide-linked homodimer of two 133 amino acid polypeptide chains.

TNF-R2 Antibody

AF0364 200ul
EUR 304
Description: TNF-R2 antibody detects endogenous levels of total TNF-R2.

TNF-R2 Antibody

AF0365 200ul
EUR 304
Description: TNF-R2 antibody detects endogenous levels of total TNF-R2.

TNF- R2 Antibody

ABF0364 100 ug
EUR 438

TNF- R2 Antibody

ABF0365 100 ug
EUR 438

ApoE R2, CF

PR15062CF 50 ug
EUR 461

R-Notoginsenoside R2

N2244-20 20 mg
EUR 572
Description: Extracted from Panax Notoginseng dried roots;Store the product in sealed, cool and dry condition

IL-8 (77 a.a.), human recombinant

P1026-1 1 mg
EUR 4226
Description: Interleukin-8 (IL-8) is a proinflammatory CXC chemokine produced by macrophages, epithelial cells. IL-8 is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies

Anti-GABAB Receptor (Ser783), R2-Subunit antibody

STJ120094 100 µl
EUR 526

Mouse Interleukin-1 beta (IL-1 beta) AssayMax ELISA Kit

EMI2200-1 96 Well Plate
EUR 477

IL-8 Interleukin-8 (1-77 a.a) Human Recombinant Protein (CXCL8)

PROTP10145-1 Regular: 25ug
EUR 317
Description: Interleukin-8 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 77 amino acids and having a molecular mass of 8904 Dalton. ;The IL-8 is purified by proprietary chromatographic techniques.

IL-1RA Interleukin-1 Receptor Antagonist Human Recombinant Protein, His Tag

PROTP18510-1 Regular: 50ug
EUR 682
Description: IL1Ra Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 152 amino acids fragment (26-177) and having a total molecular mass of 21.63kDa with an amino-terminal hexahistidine tag. ;The IL-1Ra His is purified by proprietary chromatographic techniques.

Anti-IL 1 alpha antibody

PAab04208 100 ug
EUR 386

Anti-IL-1 beta Antibody

A00101-2 1mg
EUR 1232
Description: Rabbit Polyclonal IL-1 beta Antibody. Validated in IP, IHC, WB and tested in Human.

Anti-IL-1 Alpha Antibody

A01144 1mg
EUR 1232
Description: Rabbit Polyclonal IL-1 Alpha Antibody. Validated in WB and tested in Human.

Anti-IL-1 RII antibody

STJ16100664 100 µg
EUR 742

Anti-IL-1 beta antibody

STJ73078 100 µg
EUR 359

anti- IL 1 alpha antibody

FNab04208 100µg
EUR 548.75
Description: Antibody raised against IL 1 alpha

IL-2

E13-013-1 10μg
EUR 161

IL-4

E13-015-1 10μg
EUR 161

IL-6

E13-016-1 10μg
EUR 161

IL-1-alpha Interleukin-1 alpha Mouse Recombinant Protein, His Tag

PROTP01582-1 Regular: 20ug
EUR 317
Description: IL 1 alpha Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (115-270 a.a) and having a molecular mass of 20.4kDa.;IL 1 alpha is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

IL-1-beta Interleukin-1 beta Mouse Recombinant Protein, His Tag

PROTP10749-1 Regular: 25ug
EUR 317
Description: Interleukin-1 beta Mouse Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 189 amino acids and having a molecular mass of 21 kDa. ;The IL-1b is fused to His-Tag and purified by proprietary chromatographic techniques.

IL-1-alpha Interleukin-1 alpha Rat Recombinant Protein, His Tag

PROTP16598-1 Regular: 20ug
EUR 317
Description: IL 1 alpha Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (115-270 a.a) and having a molecular mass of 20.2kDa.

Anti-IL-1F6 / IL-36

PAab04239 100 ug
EUR 412

IL-17 Interleukin-17 Human Recombinant Protein

PROTQ16552-1 Regular: 25ug
EUR 317
Description: Interleukin-17A Human Recombinant produced in E.Coli is a homodimeric, non-glycosylated polypeptide chain containing a total of 264 amino acids (2 chains of 132 aa) and having a molecular mass of 31kDa.  ;The IL-17 is purified by proprietary chromatographic techniques.

IL-29 Interleukin-29 Human Recombinant Protein

PROTQ8IU54-1 Regular: 20ug
EUR 317
Description: IL-29 human recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 181 amino acids and having a molecular mass of 20 kDa.

IL-28A Interleukin-28A Human Recombinant Protein

PROTQ8IZJ0-1 Regular: 20ug
EUR 317
Description: IL-28A human recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 175 amino acids and having a molecular mass of 19.6 kDa.

IL-17B Interleukin 17B Human Recombinant Protein

PROTQ9UHF5-1 Regular: 25ug
EUR 317
Description: Interleukin-17B Human Recombinant produced in E.Coli is a homodimeric, non-disulfide-linked polypeptide chain containing a total of 322 amino acids (2 chains of 161aa) and having a molecular mass of 36.5kDa. The IL-17B is purified by proprietary chromatographic techniques.

IL-4 Interleukin-4 Human Recombinant Protein

PROTP05112-1 Regular: 20ug
EUR 317
Description: Interleukin-4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 130 amino acids and having a molecular mass of 15kDa. ;The IL-4 is purified by proprietary chromatographic techniques.

IL-6 Interleukin-6 Human Recombinant Protein

PROTP05231-1 Regular: 20ug
EUR 317
Description: Interleukin-6 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 184 amino acids and having a molecular mass of 21000 Dalton. ;The IL6 is purified by proprietary chromatographic techniques.

IL-3 Interleukin-3 Human Recombinant Protein

PROTP08700-1 Regular: 10ug
EUR 317
Description: Interleukin-3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 133 amino acids and having a molecular mass of 15000 Dalton. The IL-3 is purified by proprietary chromatographic techniques.

IL-9 Interleukin-9 Human Recombinant Protein

PROTP15248-1 Regular: 10ug
EUR 317
Description: Interleukin-9 Human Recombinant produced in E.Coli is a single, non-glycosylated single polypeptide chain containing 127 amino acids and having a molecular mass of 14,004 Dalton. ;The IL-9 is purified by proprietary chromatographic techniques.

IL-11 Interleukin-11 Human Recombinant Protein

PROTP20809-1 Regular: 10ug
EUR 317
Description: Interleukin-11 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids and having a molecular mass of 19256.29 Dalton. ;The IL-11 is purified by proprietary chromatographic techniques.

IL-1RA Interleukin-1 Receptor Antagonist Mouse Recombinant Protein

PROTP25085-1 Regular: 20ug
EUR 317
Description: IL1 ra Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 153 amino acids and having a molecular mass of 17.4kDa. ;The IL1ra is purified by proprietary chromatographic techniques.

IL-4, murine recombinant

P1022-1 1 mg
EUR 4504
Description: IL-4 is a pleiotropic cytokine produced by activated T lymphocytes, basophils, mast cells and bone marrow stromal cells. IL-4 plays an important role in the regulation of isotype switching, differentiation of precursor T helper cells and induction of IgE production in B lymphocytes.

IL-6, rat recombinant

P1023-1 1 mg
EUR 6940
Description: Interleukin-6 (IL-6) is a pleiotropic cytokine produced by activated T cells, monocytes, fibroblasts, endothelial cells, keratinocytes and macrophages, and plays an critical role in host defense by regulating immune and inflammatory responses.

IL-7, murine recombinant

P1025-1 1 mg
EUR 6940
Description: Interleukin-7 (IL-7) is a potent lymphoid cell growth factor produced by bone marrow and thymic stromal cells, spleen cells and keratinocytes. IL7 stimulates the proliferation of Pre-B, Pro-B and early T cells.

Anti-citrulline-Histone H3-R2/R8/R17 antibody

STJ11100254 100 µl
EUR 393

Anti-Phospho-PKA R2 (S99) Rabbit Monoclonal Antibody

P03911 100ug/vial
EUR 397
Description: Rabbit Monoclonal Phospho-PKA R2 (S99) Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat.

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