January 26, 2023
sysbio

dimensional proteomic evaluation of serum exhibits immunological proteins completely expressed in sulfur mustard uncovered sufferers

Blood-Mind Barrier Protein Claudin-5 Expressed in Paired Xenopus laevis Oocytes Mediates Cell-Cell Interplay

Claudin-5 determines the sealing properties of blood-brain barrier tight junctions and its perform is impaired in neurodegenerative and neuroinflammatory problems. Specializing in the contribution of claudin-5 to the trans-interaction throughout the tight junction seal, we used Xenopus laevis oocytes as an expression system. Cells had been clustered and challenged in a novel strategy for the evaluation of claudin interplay. We evaluated the strengthening impact of claudin-5 to cell-cell-connection compared to claudin-3.

Utility of a hydrostatic stress impulse on clustered management oocyte pairs revealed a discount of contact areas. In distinction, mixtures with each oocytes expressing claudins maintained an enhanced connection between the cells (cldn5-cldn5, cldn3-cldn3). Energy of interplay was elevated by each claudin-Three and claudin-5.

This novel strategy allowed an evaluation of single claudins contributing to tight junction integrity, characterizing homophilic and hetrophilic trans-interaction of claudins. To check a brand new screening strategy for barrier effectors, exemplarily, this 2-cell mannequin of oocytes was used to investigate the impact of the absorption enhancer sodium caprate on the oocyte pairs.

Two dimensional proteomic evaluation of serum exhibits immunological proteins completely expressed in sulfur mustard uncovered sufferers with long run pulmonary problems

Background: Regardless of greater than 30 years after utilization of sulfur mustard or bis (2-chloroethyl) sulfide (SM) by Iraqi troops towards Iranian army members and civilians, there are a whole lot of reported delayed problems for the uncovered folks. Nonetheless, the molecular mechanism of motion from this chemical warfare agent just isn’t acknowledged but.

Materials and technique: On this examine, we employed two dimensional gel electrophoresis (2DE) method to analyze the serum proteins from chemical uncovered folks in comparison with non-exposed people to offer an inside into molecular mechanism of this chemical agent. Every group was divided into two subgroups together with people with, and with out respiratory problems. For every group, 10 people had been included after knowledgeable consent.

End result: The outcomes confirmed protein spots, which had been completely/primarily expressed in chemical uncovered sufferers with problems, together with T cell receptor alpha, and hematopoietic cell sign transducer. Additionally there have been protein spots that had been expressed solely in all uncovered teams (with and with out problems). Alternatively, we might determine protein spots that had been completely expressed/altered solely in non-exposed group with problems together with Pre T-cell antigen receptor, CD40 ligand, and multidrug and toxin extrusion proteins.

Conclusion: Our investigation might lead to identification of proteins which are related to chemical publicity, in addition to these particular for respiratory problems no matter chemical publicity. These candidate proteins can be utilized as biomarker, in addition to a base for understanding the molecular mechanism of this chemical agent.

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Anti-CD163

DB-045-0.5 500 μl
EUR 460.8
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-CD163

DB-045-1 1 ml
EUR 735.6
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-CD163

DB-045-RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD163

DB-045-RTU-7 7 ml
EUR 277.2
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD163

DB045RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD163

DB045RTU-7 7 ml
EUR 277.2
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Mouse Cluster Of Differentiation (CD163) ELISA Kit

DLR-CD163-Mu-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Cluster Of Differentiation (CD163) in samples from serum, plasma or other biological fluids.

Mouse Cluster Of Differentiation (CD163) ELISA Kit

DLR-CD163-Mu-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Cluster Of Differentiation (CD163) in samples from serum, plasma or other biological fluids.

Rat Cluster Of Differentiation (CD163) ELISA Kit

DLR-CD163-Ra-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Rat Cluster Of Differentiation (CD163) in samples from serum, plasma, tissue homogenates or other biological fluids.

Rat Cluster Of Differentiation (CD163) ELISA Kit

DLR-CD163-Ra-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Rat Cluster Of Differentiation (CD163) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse Cluster Of Differentiation (CD163) ELISA Kit

RDR-CD163-Mu-48Tests 48 Tests
EUR 640.8

Mouse Cluster Of Differentiation (CD163) ELISA Kit

RDR-CD163-Mu-96Tests 96 Tests
EUR 890.4

Rat Cluster Of Differentiation (CD163) ELISA Kit

RDR-CD163-Ra-48Tests 48 Tests
EUR 640.8

Rat Cluster Of Differentiation (CD163) ELISA Kit

RDR-CD163-Ra-96Tests 96 Tests
EUR 890.4

Mouse Cluster Of Differentiation (CD163) ELISA Kit

RD-CD163-Mu-48Tests 48 Tests
EUR 613.2

Mouse Cluster Of Differentiation (CD163) ELISA Kit

RD-CD163-Mu-96Tests 96 Tests
EUR 850.8

Rat Cluster Of Differentiation (CD163) ELISA Kit

RD-CD163-Ra-48Tests 48 Tests
EUR 613.2

Rat Cluster Of Differentiation (CD163) ELISA Kit

RD-CD163-Ra-96Tests 96 Tests
EUR 850.8

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 418.8

Anti-CD163 Antibody

A00812-1 100ug/vial
EUR 400.8

Anti-CD163 Antibody

PA1874 100ug/vial
EUR 352.8

Anti-CD163 Antibody

PA1874-1 100ug/vial
EUR 400.8

Anti-CD163 antibody

STJ110681 100 µl
EUR 332.4
Description: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Anti-CD163 Antibody

STJ500423 100 µg
EUR 571.2

Anti-CD163 Antibody

STJ500424 100 µg
EUR 571.2

Anti-CD163 antibody

STJ160082 1 mL C
EUR 1129.2

Anti-CD163 antibody

STJ16100302 100 µg
EUR 864

Anti-CD163 antibody

STJ16100324 1 mL
EUR 1174.8

Anti-CD163 antibody

STJ180301 0.1 ml
EUR 258

Anti-CD163 antibody

STJ190009 200 µl
EUR 236.4
Description: Unconjugated Mouse monoclonal to CD163 (AS1A1)

Human CD163 antigen(CD163)ISA kit

GA-E0263HM-48T 48T
EUR 346.8

Human CD163 antigen(CD163)ISA kit

GA-E0263HM-96T 96T
EUR 559.2

human CD163 antigen,CD163 LISA kit

201-12-0247 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human CD163 antigen(CD163)ISA kit

QY-E05066 96T
EUR 433.2

Anti-Hu CD163 PE

1P-645-T025 25 tests
EUR 168

Anti-Hu CD163 PE

1P-645-T100 100 tests
EUR 288

Anti-Hu CD163 Purified

11-645-C025 0.025 mg
EUR 118.8

Anti-Hu CD163 Purified

11-645-C100 0.1 mg
EUR 189.6

Anti-Hu CD163 APC

1A-645-T025 25 tests
EUR 168

Anti-Hu CD163 APC

1A-645-T100 100 tests
EUR 288

Anti-CD163/M130 Antibody

A00812 100ul
EUR 476.4
Description: Rabbit IgG polyclonal antibody for Scavenger receptor cysteine-rich type 1 protein M130 (CD163) detection.tested for IF, IHC, WB in Human, Mouse, Rat. Various direct flourescent conjugates are available for FCM upon request. Please contact us for details.

anti- CD163/M130 Antibody

FNab09771 100µg
EUR 658.5
Description: Antibody raised against CD163/M130 

Anti-CD163/M130 antibody

PAab09771 100 ug
EUR 426

Anti-CD163 Antibody BIOTIN

STJ500425 100 µg
EUR 703.2

Anti-CD163 Antibody FITC

STJ500426 100 µg
EUR 703.2

Anti-CD163 Antibody BIOTIN

STJ500427 100 µg
EUR 703.2

Anti-CD163 Antibody FITC

STJ500428 100 µg
EUR 703.2

Mouse Anti Human Cd163 Monoclonal Antibody

CABT-47162MH 25 µg
EUR 446.4

Mouse Anti Human Cd163 Monoclonal Antibody

CABT-47163MH 0.2 mg
EUR 1057.2

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 336

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 336

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 336

Anti-CD163 Rabbit Monoclonal Antibody

M00812 100ug/vial
EUR 476.4
Description: Rabbit Monoclonal CD163 Antibody. Validated in IP, WB and tested in Human.

Anti-Hu CD163 PE-Cy7

T7-645-T025 25 tests
EUR 184.8

Anti-Hu CD163 PE-Cy7

T7-645-T100 100 tests
EUR 321.6

Anti-Hu CD163 PerCP-Cy5.5

T9-645-T025 25 tests
EUR 235.2

Anti-Hu CD163 PerCP-Cy5.5

T9-645-T100 100 tests
EUR 422.4

Purified Anti-human CD163 Antibody *GHI/61*

11630000 100 ug
EUR 365

APC Anti-human CD163 Antibody *GHI/61*

116301B0 25 tests
EUR 383

APC Anti-human CD163 Antibody *GHI/61*

116301B1 100 tests
EUR 995

APC Anti-human CD163 Antibody *GHI/61*

116301B2 500 tests
EUR 2984

FITC Anti-human CD163 Antibody *GHI/61*

116301G0 100 tests
EUR 547

FITC Anti-human CD163 Antibody *GHI/61*

116301G1 500 tests
EUR 2051

TRITC Anti-human CD163 Antibody *GHI/61*

116301H0 100 tests
EUR 547

TRITC Anti-human CD163 Antibody *GHI/61*

116301H1 500 tests
EUR 2051

PacBlue Anti-human CD163 Antibody *GHI/61*

116301I0 100 tests
EUR 547

PacBlue Anti-human CD163 Antibody *GHI/61*

116301I1 500 tests
EUR 2051

PacOrange Anti-human CD163 Antibody *GHI/61*

116301J0 100 tests
EUR 547

PacOrange Anti-human CD163 Antibody *GHI/61*

116301J1 500 tests
EUR 2051

PE Anti-human CD163 Antibody *GHI/61*

116301K0 25 tests
EUR 383

PE Anti-human CD163 Antibody *GHI/61*

116301K1 100 tests
EUR 995

PE Anti-human CD163 Antibody *GHI/61*

116301K2 500 tests
EUR 2984

PerCP Anti-human CD163 Antibody *GHI/61*

116301S0 25 tests
EUR 383

PerCP Anti-human CD163 Antibody *GHI/61*

116301S1 100 tests
EUR 995

PerCP Anti-human CD163 Antibody *GHI/61*

116301S2 500 tests
EUR 2984

Canine CD163 antigen(CD163 LISA kit

GA-E0062CN-48T 48T
EUR 482.4

Canine CD163 antigen(CD163 LISA kit

GA-E0062CN-96T 96T
EUR 820.8

Porcine CD163 antigen,CD163 LISA kit

GA-E0045PC-48T 48T
EUR 436.8

Porcine CD163 antigen,CD163 LISA kit

GA-E0045PC-96T 96T
EUR 708

CD163 Antibody

1-CSB-PA969205
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100

CD163 Antibody

DF8235 200ul
EUR 420

CD163 siRNA

20-abx910930
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

CD163 siRNA

20-abx910931
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

Cd163 Antibody

1-CSB-PA650452LA01MO
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Cd163. Recognizes Cd163 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:500-1:2000

CD163 Antibody

1-CSB-PA801238LA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF; Recommended dilution: IF:1:50-1:200

CD163 Antibody

49553-100ul 100ul
EUR 399.6

CD163 Antibody

49553-50ul 50ul
EUR 286.8

CD163 Antibody

37157-100ul 100ul
EUR 302.4

CD163 antibody

10R-6496 100 ug
EUR 243.6
Description: Mouse monoclonal CD163 antibody

CD163 antibody

10R-CD163aRT 250 ug
EUR 859.2
Description: Mouse monoclonal CD163 antibody

CD163 Antibody

ABD8235 100 ug
EUR 525.6

CD163 Antibody

20-abx242956
  • EUR 560.40
  • EUR 393.60
  • 100 ul
  • 50 ul

CD163 Antibody

R30973 100 ug
EUR 419

CD163 Antibody

R30974 100 ug
EUR 419

CD163 Antibody

RQ4259 100 ug
EUR 419

CD163 Antibody

V8227-100UG 100 ug
EUR 499
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V8227-20UG 20 ug
EUR 219
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V8227SAF-100UG 100 ug
EUR 499
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V8415-100UG 100 ug
EUR 499
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

Quantitative evaluation of differentially expressed proteins in psoriasis vulgaris utilizing tandem mass tags and parallel response monitoring

Background: Psoriasis vulgaris (PV) is a continual autoimmune inflammatory illness with epidermal hyperkeratosis and parakeratosis.

Strategies: The examine was to elucidate the pathogenesis of PV by quantitative proteomic evaluation of pores and skin lesion biopsies of PV and wholesome tissues with tandem mass tags (TMTs) coupled with liquid chromatography-mass spectrometry (LC-MS)/MS.

Outcomes: A complete of 4562 differentially expressed proteins (DEPs) between PV lesional tissues (n = 11) and wholesome tissues (n = 11) had been recognized, of which 299 had been upregulated and 206 had been downregulated utilizing |fold change| > 1.Three because the cutoff threshold.

The Gene Ontology (GO) annotation and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment evaluation revealed that the DEPs had been primarily enriched within the activation of immune cells (drug metabolism pathway, NOD-like pathway, and IL-17 pathway), cell proliferation (ribosomal pathway, DNA replication pathway, and base replication pathway), metabolism-related pathways (fatty acid biosynthesis and metabolism, PPAR pathway, glycerophospholipid metabolism, and cortisol synthesis and breakdown), and glandular secretion (saliva secretion, gastric acid secretion, and pancreatic fluid secretion).

13 DEPs that had been comparatively extremely expressed within the drug metabolism pathway had been validated with parallel response monitoring (PRM), of which MPO, TYMP, IMPDH2, GSTM4, and ALDH3A1 had been extremely expressed in PV, whereas CES1, MAOB, MGST1, and GSTT1 had been much less expressed in PV.

Conclusions: These findings confirmed that these proteins take part within the drug metabolism-other enzyme pathways and play essential roles within the activation and proliferation of immune cells within the pathogenesis of PV.

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 336

IL-1 R2 ELISA Kit (Human) : 96 Wells (OKAG00129)

OKAG00129 96 Wells
EUR 715.2
Description: Description of target: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.;Species reactivity: Human;Application: ELISA;Assay info: Quantitative Colorimentric Sandwich ELISA;Sensitivity: 32 pg/mL

Anti-IL1R2/Il 1 Rii Antibody

A03106-1 1 ml
EUR 476.4
Description: Rabbit Polyclonal IL1R2/Il 1 Rii Antibody. Validated in IP, WB and tested in Human.

anti-PKA R2

YF-PA24454 50 ul
EUR 400.8
Description: Mouse polyclonal to PKA R2

anti-PKA R2

YF-PA13990 50 ul
EUR 435.6
Description: Mouse polyclonal to PKA R2

Anti-IL-31 Antibody

A08339-1 100ug/vial
EUR 400.8

Anti-IL-17B Antibody

A10846-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for IL-17B Antibody (IL17B) detection.tested for IHC in Human, Rat.

Anti-IL-6 Antibody

A00102-1 100ug
EUR 518.4
Description: Rabbit Polyclonal IL-6 Antibody. Validated in Neu, IHC, WB and tested in Human.

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 418.8

Anti-MonoMethylH3R2me1-(R2) antibody

STJ24010 100 µl
EUR 471.6
Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Anti-TNF-R2 antibody

STJ96053 200 µl
EUR 236.4
Description: Rabbit polyclonal to TNF-R2.

Anti-GABAB R2 antibody

STJ96379 200 µl
EUR 236.4
Description: Rabbit polyclonal to GABAB R2.

Anti-PKA R2 (3C7)

YF-MA14876 100 ug
EUR 435.6
Description: Mouse monoclonal to PKA R2

Anti-PKA R2 (6A9)

YF-MA10721 100 ug
EUR 435.6
Description: Mouse monoclonal to PKA R2

Anti-IL-3R beta Antibody

A02219-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for IL-3R beta Antibody (CSF2RB) detection.tested for WB in Human, Mouse, Rat.

Anti-IL-2/IL2 Antibody

A00387-1 100ug/vial
EUR 352.8

Anti-IL-8 Monoclonal Antibody

A00423-1 100ul
EUR 476.4
Description: Mouse Monoclonal Antibody for IL-8 Antibody (CXCL8) detection. Tested with IHC in Human, Mouse, Rat.

Anti-IL-22/IL22 Antibody

A00963-1 100ug/vial
EUR 352.8

Anti-IL-6 Monoclonal Antibody

M00102-1 100ug
EUR 546
Description: Mouse Monoclonal IL-6 Antibody. Validated in Flow Cytometry, WB and tested in Human.

Anti-IL-17A Monoclonal Antibody

M00421-1 100ug
EUR 546
Description: Mouse Monoclonal IL-17A Antibody. Validated in WB and tested in Human.

Rat Anti-Mouse IL-12 p75 Monoclonal antibody, clone R2-9A5

CABT-L4486-1mg 1 mg
EUR 1076.4

Rat Anti-Mouse IL-12 p75 Monoclonal antibody, clone R2-9A5

CABT-L4486-5mg 5 mg
EUR 2886

Anti-Human IL-17F Biotin Conjugated Monoclonal Antibody

B02062-1 100ug
EUR 518.4
Description: Mouse Monoclonal Human IL-17F Biotin Conjugated Antibody. Validated in IHC, WB and tested in Human.

IL-1 β

E13-003-1 10μg
EUR 255.6

IL-1 α

E13-029-1 10μg
EUR 255.6

Anti-IL-32A Antibody Peroxidase Conjugated

A03286-1 100ug
EUR 546
Description: Rabbit Polyclonal IL-32A Antibody Peroxidase Conjugated. Validated in WB and tested in Human.

IL-1 beta, rat recombinant

P1019-1 1 mg
EUR 8745.6
Description: Interleukin 1 beta (IL-1?) is a proinflammatory cytokine and is produced by activated macrophages, monocytes, keratinocytes and other epithelial cells. Both IL-1? and IL-1? bind to the same receptor and have similar biological properties.

Anti-GABA(B) R2 Purified

11-551-C100 0.1 mg
EUR 244.8

IL-1beta, human recombinant

P1018-1 1 mg
EUR 6073.2
Description: Interleukin 1 beta (IL-1?) is a proinflammatory cytokine and is produced by activated macrophages, monocytes, keratinocytes and other epithelial cells

IL-2, human recombinant

P1020-1 1 mg
EUR 1387.2
Description: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes and is produced by activated CD4+ and CD8+ T cells, gamma ? T cells, B cells, dendritic cells and eosinophils. IL-2 plays a critical role in immune responses against pathogenic infection

IL-3, human recombinant

P1021-1 1 mg
EUR 4820.4
Description: Interleukin 3 (IL-3) is a pleiotropic cytokine produced by activated T cells, mast cells and eosinophils, and stimulates the proliferation and differentiation of pluripotent hematopoietic stem cells, and committed progenitor cells of the megakaryocyte

IL-7, human recombinant

P1024-1 1 mg
EUR 8328
Description: Interleukin-7 (IL-7) is a potent lymphoid cell growth factor produced by bone marrow and thymic stromal cells, spleen cells and keratinocytes. IL7 stimulates the proliferation of Pre-B, Pro-B and early T cells.

Human Interleukin-1 beta (IL-1 beta) AssayMax ELISA Kit

EI2200-1 96 Well Plate
EUR 572.4

Human Interleukin-1-alpha (IL-1-alpha) AssayMax ELISA Kit

EI2301-1 96 Well Plate
EUR 572.4

Notoginsenoside R2

HY-N0909 10mg
EUR 555.6

Stipuleanoside R2

TBZ1475 unit Ask for price

Notoginsenoside R2

TN028181 20mg Ask for price

Recombinant Rat IL-1 Beta Protein

PROTQ63264-1 10ug
EUR 380.4
Description: IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant rat IL-1β is a 17.4 kDa protein containing 153 amino acid residues.

Canine IL-1 beta Recombinant Protein

R00101-1 5ug/vial
EUR 310.8
Description: IL-1 beta (IL-1β) is a member of the interleukin 1 family of cytokines. The IL-1 beta cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Canine IL-1 beta Recombinant Protein is purified interleukin-1 beta cytokine produced in yeast.

Canine IL-1 alpha Recombinant Protein

R01144-1 5ug/vial
EUR 310.8
Description: IL-1 alpha (IL-1α, IL-1F1) is a member of the interleukin 1 family of cytokines. IL-1 alpha is an inflammatory cytokine active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. Canine IL-1 alpha Recombinant Protein is purified interleukin-1 alpha cytokine produced in yeast.

HRP-Goat Anti-Mouse Secondary Antibody

A12003
  • EUR 232.26
  • EUR 117.70
  • 350 µg
  • 350 ug

HRP-Goat Anti-Rabbit Secondary Antibody

A12004
  • EUR 232.26
  • EUR 117.70
  • 350 µg
  • 350 ug

IL-1-alpha Interleukin-1 alpha Human Recombinant Protein, His Tag

PROTP01583-1 Regular: 20ug
EUR 380.4
Description: IL-1A Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 159 amino acids fragment (113-271) with an amino-terminal hexahistidine tag and having a total molecular mass of 22.5kDa. ;The Interleukin-1 alpha His-tag is purified by proprietary chromatographic techniques.

IL-10, human recombinant protein

P1028-1 1 mg
EUR 8077.2
Description: Interleukin-10 (IL-10) is an immunosuppressive cytokine produced by macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the synthesis of proinflammatory cytokines such as IL-1 and TNF-? and proliferation of T cells

IL-15, human recombinant protein

P1029-1 1 mg
EUR 6406.8
Description: Interleukin 15 (IL-15) is an immunomodulating cytokine mainly produced by adherent peripheral blood mononuclear cells, fibroblasts and epithelial cells and stimulates the proliferation of T lymphocytes.

IL-17A, human recombinant protein

P1030-1 1 mg
EUR 4987.2
Description: Interleukin-17A (IL-17A) is a proinflammatory cytokine produced by Th17 cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases and stimulates the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as the production of nitric oxide (NO).

IL-18, human recombinant protein

P1032-.1 100 µg
EUR 936
Description: Interleukin-18 (IL-18) is a proinflammatory cytokine produced by monocyte/macrophages, osteoblasts and keratinocytes, as a proprotein which is proteolytically processed to its active form by caspase-1. Human IL-18 can enhance NK cell activity in PBMC cultures.

IL-18, human recombinant protein

P1032-1 1 mg
EUR 6073.2
Description: Interleukin-18 (IL-18) is a proinflammatory cytokine produced by monocyte/macrophages, osteoblasts and keratinocytes, as a proprotein which is proteolytically processed to its active form by caspase-1. Human IL-18 can enhance NK cell activity in PBMC cultures.

IL-21, human recombinant protein

P1033-1 1 mg
EUR 7826.4
Description: Interleukin-21 (IL-21) is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. IL-21 induces the differentiation of T-cell-stimulated B-cells into plasma cells and memory B-cells, apoptotic effects in naïve B-cells.

Recombinant Human IL-24 Protein

PROTQ13007-1 20ug
EUR 380.4
Description: IL-24 is a secreted glycoprotein belonging to the IL-10 structural family of cytokines. It is produced by a variety of cell types, including B cells, CD4+ cells, NK cells, lymph node DCs, monocytes, and melanoma cells. IL-24 can signal through the IL20R1/IL20R2 and IL22R1/IL20R2 receptors to initiate a signaling cascade which includes the induction of JAK1/STAT3 phosphorylation. IL-24 is, functionally, a pleiotropic protein but is generally characterized as an anti-cancer cytokine that can selectively inhibit growth of a wide variety of human cancer cells through activities that include the induction of differentiation and apoptosis, and the suppression of angiogenesis and cell proliferation. Recombinant human IL-24 is an 18.9 kDa glycoprotein, containing 161 amino acid residues, including a C-terminal His-tag.

Recombinant Human IL-31 Protein

PROTQ6EBC2-1 10ug
EUR 380.4
Description: Human IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant IL-31 is a 15.8 kDa protein containing 141 amino acid residues.

Recombinant Human IL-17D Protein

PROTQ8TAD2-1 25ug
EUR 380.4
Description: IL-17D is a disulfide-linked homodimer of two 185 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17D has the ability to stimulate the production of IL-6, IL-8, and GM-CSF and inhibits hemopoiesis of myeloid progenitor cells in colony forming assays. Recombinant human IL-17D is a 40.5 kDa disulfide-linked homodimer of two 185 amino acid polypeptide chains.

Recombinant Human IL-22 Protein

PROTQ9GZX6-1 10ug
EUR 380.4
Description: IL-22 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10R-β/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family. Recombinant human IL-22 is a 33.6 kDa non-disulfide-linked homodimeric protein containing of two 146 amino acid polypeptide chains.

Recombinant Human IL-17E Protein

PROTQ9H293-1 25ug
EUR 380.4
Description: IL-17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulated secretion of IL-8, and induces activation of the transcription factor NF-κB in cells that express the IL-17BR receptor. Recombinant human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 145 amino acid polypeptide chains.

Recombinant Human IL-20 Protein

PROTQ9NYY1-1 10ug
EUR 380.4
Description: IL-20 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. IL-20 signals through a receptor system composed of type I IL-20R-α and type II IL-20R-β. Over-expression of IL-20 in keratinocytes expressing both receptor subunits has been implicated in the induction of inflammatory skin disease. Recombinant human IL-20 is a 35.2 kDa homodimeric protein consisting of two 153 amino acid polypeptide chains.

Recombinant Human IL-19 Protein

PROTQ9UHD0-1 10ug
EUR 380.4
Description: IL-19 belongs to the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. Preliminary data suggests that IL-19 is a proinflammatory cytokine because it up-regulates IL-6 and TNF-α and induces apoptosis through TNF-α. IL-19 signals through the type I IL-20R. Human and murine IL-19 share 71% amino acid sequence identity. Recombinant human IL-19 is a 17.9 kDa protein containing 153 amino acid residues. In solution IL-19 exists predominantly as a non-disulfide-linked dimer.

Recombinant Human IL-12 Protein

PROTP29459-1 10ug
EUR 380.4
Description: IL-12 is a potent regulator of cell mediated immune responses and it induces IFN-γ production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue type mast cells. Among its biological activities IL-12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells and induces the development of IFN-γ producing Th1 cells. Recombinant Human IL-12 is a 75.0 kDa heterodimeric glycoprotein consisting of disulfide-linked 35 kDa (p35) and 40 kDa (p40) subunits (503 total amino acid residues).

IL-1-beta Interleukin-1 betaHuman Recombinant Protein

PROTP01584-1 Regular: 10ug
EUR 380.4
Description: Interleukin-1 beta Human Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 153 amino acids and having a molecular mass of 17000 Dalton.;The IL-1b is purified by proprietary chromatographic techniques.

Goat Anti-Rabbit Secondary Antibody, Biotin Conjugated

A12001
  • EUR 232.26
  • EUR 117.70
  • 350 µg
  • 350 ug

Goat Anti-Rat Secondary Antibody, Biotin Conjugated

A12002
  • EUR 232.26
  • EUR 117.70
  • 350 µg
  • 350 ug

Recombinant Murine IL-17 (IL-17A) Protein

PROTQ62386-1 25ug
EUR 380.4
Description: The originally described IL-17 protein, now known as IL-17A, is a disulfide linked homodimer, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells. Recombinant murine IL-17A is a 30.0 kDa disulfide-linked homodimer of two 133 amino acid polypeptide chains.

Anti-Phospho-GABAB R2 (Ser783) Antibody

P03830 100ul
EUR 477.6
Description: Rabbit Polyclonal Phospho-GABAB R2 (Ser783) Antibody. Validated in IF, WB and tested in Mouse, Rat.

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 336

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 336

IL-8 (77 a.a.), human recombinant

P1026-1 1 mg
EUR 5071.2
Description: Interleukin-8 (IL-8) is a proinflammatory CXC chemokine produced by macrophages, epithelial cells. IL-8 is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies

PKA R2 Antibody

DF3091 200ul
EUR 420

PKA R2 Antibody

AF6724 100ul
EUR 420

TNF- R2 Antibody

ABF0364 100 ug
EUR 525.6

TNF- R2 Antibody

ABF0365 100 ug
EUR 525.6

R-Notoginsenoside R2

N2244-20 20 mg
EUR 686.4
Description: Extracted from Panax Notoginseng dried roots;Store the product in sealed, cool and dry condition

ApoE R2, CF

PR15062CF 50 ug
EUR 553.2

Porphyromonas gingivalis Gingipain R2 (rgpB)

1-CSB-EP310587EYA
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Porphyromonas gingivalis Gingipain R2(rgpB),partial expressed in E.coli

IL-8 Interleukin-8 (1-77 a.a) Human Recombinant Protein (CXCL8)

PROTP10145-1 Regular: 25ug
EUR 380.4
Description: Interleukin-8 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 77 amino acids and having a molecular mass of 8904 Dalton. ;The IL-8 is purified by proprietary chromatographic techniques.

IL-1RA Interleukin-1 Receptor Antagonist Human Recombinant Protein, His Tag

PROTP18510-1 Regular: 50ug
EUR 818.4
Description: IL1Ra Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 152 amino acids fragment (26-177) and having a total molecular mass of 21.63kDa with an amino-terminal hexahistidine tag. ;The IL-1Ra His is purified by proprietary chromatographic techniques.

Mouse Interleukin-1 beta (IL-1 beta) AssayMax ELISA Kit

EMI2200-1 96 Well Plate
EUR 572.4

IL-2

E13-013-1 10μg
EUR 193.2

IL-4

E13-015-1 10μg
EUR 193.2

IL-6

E13-016-1 10μg
EUR 193.2

Human Genomic DNA 

X11000
  • Ask for price
  • EUR 235.40
  • 0.2 ml
  • 0.2 ml

IL-17 Interleukin-17 Human Recombinant Protein

PROTQ16552-1 Regular: 25ug
EUR 380.4
Description: Interleukin-17A Human Recombinant produced in E.Coli is a homodimeric, non-glycosylated polypeptide chain containing a total of 264 amino acids (2 chains of 132 aa) and having a molecular mass of 31kDa.  ;The IL-17 is purified by proprietary chromatographic techniques.

IL-29 Interleukin-29 Human Recombinant Protein

PROTQ8IU54-1 Regular: 20ug
EUR 380.4
Description: IL-29 human recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 181 amino acids and having a molecular mass of 20 kDa.

IL-28A Interleukin-28A Human Recombinant Protein

PROTQ8IZJ0-1 Regular: 20ug
EUR 380.4
Description: IL-28A human recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 175 amino acids and having a molecular mass of 19.6 kDa.

IL-17B Interleukin 17B Human Recombinant Protein

PROTQ9UHF5-1 Regular: 25ug
EUR 380.4
Description: Interleukin-17B Human Recombinant produced in E.Coli is a homodimeric, non-disulfide-linked polypeptide chain containing a total of 322 amino acids (2 chains of 161aa) and having a molecular mass of 36.5kDa. The IL-17B is purified by proprietary chromatographic techniques.

IL-6 Interleukin-6 Human Recombinant Protein

PROTP05231-1 Regular: 20ug
EUR 380.4
Description: Interleukin-6 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 184 amino acids and having a molecular mass of 21000 Dalton. ;The IL6 is purified by proprietary chromatographic techniques.

IL-3 Interleukin-3 Human Recombinant Protein

PROTP08700-1 Regular: 10ug
EUR 380.4
Description: Interleukin-3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 133 amino acids and having a molecular mass of 15000 Dalton. The IL-3 is purified by proprietary chromatographic techniques.

IL-9 Interleukin-9 Human Recombinant Protein

PROTP15248-1 Regular: 10ug
EUR 380.4
Description: Interleukin-9 Human Recombinant produced in E.Coli is a single, non-glycosylated single polypeptide chain containing 127 amino acids and having a molecular mass of 14,004 Dalton. ;The IL-9 is purified by proprietary chromatographic techniques.

IL-11 Interleukin-11 Human Recombinant Protein

PROTP20809-1 Regular: 10ug
EUR 380.4
Description: Interleukin-11 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids and having a molecular mass of 19256.29 Dalton. ;The IL-11 is purified by proprietary chromatographic techniques.

IL-4 Interleukin-4 Human Recombinant Protein

PROTP05112-1 Regular: 20ug
EUR 380.4
Description: Interleukin-4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 130 amino acids and having a molecular mass of 15kDa. ;The IL-4 is purified by proprietary chromatographic techniques.

Anti-GABAB Receptor (Ser783), R2-Subunit antibody

STJ120094 100 µl
EUR 631.2

IL-4, murine recombinant

P1022-1 1 mg
EUR 5404.8
Description: IL-4 is a pleiotropic cytokine produced by activated T lymphocytes, basophils, mast cells and bone marrow stromal cells. IL-4 plays an important role in the regulation of isotype switching, differentiation of precursor T helper cells and induction of IgE production in B lymphocytes.

IL-6, rat recombinant

P1023-1 1 mg
EUR 8328
Description: Interleukin-6 (IL-6) is a pleiotropic cytokine produced by activated T cells, monocytes, fibroblasts, endothelial cells, keratinocytes and macrophages, and plays an critical role in host defense by regulating immune and inflammatory responses.

IL-7, murine recombinant

P1025-1 1 mg
EUR 8328
Description: Interleukin-7 (IL-7) is a potent lymphoid cell growth factor produced by bone marrow and thymic stromal cells, spleen cells and keratinocytes. IL7 stimulates the proliferation of Pre-B, Pro-B and early T cells.

Human Brain Genomic DNA  

X11001
  • Ask for price
  • EUR 77.00
  • 10 µg
  • 10 ul

IL-1-beta Interleukin-1 beta Mouse Recombinant Protein, His Tag

PROTP10749-1 Regular: 25ug
EUR 380.4
Description: Interleukin-1 beta Mouse Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 189 amino acids and having a molecular mass of 21 kDa. ;The IL-1b is fused to His-Tag and purified by proprietary chromatographic techniques.

IL-1-alpha Interleukin-1 alpha Rat Recombinant Protein, His Tag

PROTP16598-1 Regular: 20ug
EUR 380.4
Description: IL 1 alpha Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (115-270 a.a) and having a molecular mass of 20.2kDa.

IL-1-alpha Interleukin-1 alpha Mouse Recombinant Protein, His Tag

PROTP01582-1 Regular: 20ug
EUR 380.4
Description: IL 1 alpha Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (115-270 a.a) and having a molecular mass of 20.4kDa.;IL 1 alpha is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

IL-1RA Interleukin-1 Receptor Antagonist Mouse Recombinant Protein

PROTP25085-1 Regular: 20ug
EUR 380.4
Description: IL1 ra Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 153 amino acids and having a molecular mass of 17.4kDa. ;The IL1ra is purified by proprietary chromatographic techniques.

anti- IL 1 alpha antibody

FNab04208 100µg
EUR 658.5
Description: Antibody raised against IL 1 alpha

Anti-IL-1 Alpha Antibody

A01144 1mg
EUR 1478.4
Description: Rabbit Polyclonal IL-1 Alpha Antibody. Validated in WB and tested in Human.

Anti-IL-1 beta Antibody

A00101-2 1mg
EUR 1478.4
Description: Rabbit Polyclonal IL-1 beta Antibody. Validated in IP, IHC, WB and tested in Human.

Anti-IL 1 alpha antibody

PAab04208 100 ug
EUR 463.2

Anti-IL-1 RII antibody

STJ16100664 100 µg
EUR 890.4

Anti-IL-1 beta antibody

STJ73078 100 µg
EUR 430.8

Human Interleukin-6 (IL-6) AssayMax ELISA Kit

EI1006-1 96 Well Plate
EUR 572.4

Human Interleukin-8 (IL-8) AssayMax ELISA Kit

EI1008-1 96 Well Plate
EUR 572.4

Human Interleukin-10 (IL-10) AssayMax ELISA Kit

EI3010-1 96 Well Plate
EUR 572.4

Human Interleukin-15 (IL-15) AssayMax ELISA Kit

EI3015-1 96 Well Plate
EUR 572.4

Human Interleukin-33 (IL-33) AssayMax ELISA Kit

EI3033-1 96 Well Plate
EUR 572.4

IL-10 Interleukin-10 Human Recombinant Protein, His

PROTP22301-1 Regular: 10ug
EUR 380.4
Description: Interleukin-10 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 181 amino acids fragment (19-178) and having a total molecular mass of 20.94kDa with a 20 amino acids N-Terminal His tag. ;The IL-10 His-Tag protein is purified by proprietary chromatographic techniques.

Anti-IL-1F6 / IL-36

PAab04239 100 ug
EUR 494.4

His-IL-3

E13-014-1 10μg
EUR 193.2

His-IL-10

E13-019-1 10μg
EUR 193.2

His-IL-22

E13-028-1 10μg
EUR 255.6

IL-2-Fc

E13-m007-1 10μg
EUR 372

IL-17A, rat recombinant protein

P1031-1 1 mg
EUR 4987.2
Description: Interleukin-17A (IL-17A) is a proinflammatory cytokine produced by Th17 cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases and stimulates the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as the production of nitric oxide (NO)

Recombinant Rat IL-5 Protein

PROTQ08125-1 10ug
EUR 380.4
Description: IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Recombinant rat IL-5 is a 26.0 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.

Recombinant Murine IL-31 Protein

PROTQ6EAL8-1 10ug
EUR 380.4
Description: IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant murine IL-31 is a 15.8 kDa protein containing 140 amino acid residues.

Recombinant Murine IL-17F Protein

PROTQ7TNI7-1 25ug
EUR 380.4
Description: IL-17F, a member of the IL-17 family of structurally related cytokines, has been shown to stimulate proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis. Recombinant murine IL-17F is a disulfide-linked homodimer of 30 kDa, consisting of two 134 amino acid residue chains.

Recombinant Murine IL-21 Protein

PROTQ9ES17-1 10ug
EUR 380.4
Description: IL-21 is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. Its action generally enhances antigen-specific responses of immune cells. The biological effects of IL-21 include induction of differentiation of T-cells-stimulated-B-cells into plasma cells and memory B-cells, stimulation (in conjunction) with IL-4 of IgG production, and induction of apoptotic effects in naïve B-cells and stimulated B-cells in the absence of T-cell signaling. Additionally, IL-21 promotes the anti-tumor activity of CD8+ T-cells and NK cells. IL-21 exerts its effect through binding to a specific type I cytokine receptor, IL-21R, which also contains the γ chain (γc) found in other cytokine receptors including IL-2, IL-4, IL-7, IL-9 and IL-15. The IL-21/IL-21R interaction triggers a cascade of events which includes activation of the tyrosine kinases JAK1 and JAK3, followed by activation of the transcription factors STAT1 and STAT3. Recombinant murine IL-21 is a 15.0 kDa protein consisting of 130 amino acid residues.

Recombinant Murine IL-4 Protein

PROTP07750-1 20ug
EUR 380.4
Description: IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant murine IL-4 is a 13.5 kDa globular protein containing 121 amino acid residues.

Recombinant Murine IL-7 Protein

PROTP10168-1 10ug
EUR 380.4
Description: IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant murine IL-7 is a 15.0 kDa protein containing 130 amino acid residues.

Recombinant Murine IL-9 Protein

PROTP15247-1 10ug
EUR 380.4
Description: IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes. IL-9 enhances the proliferation of T lymphocytes, mast cells, erthroid precursor cells and megakaryoblastic leukemia cell lines. Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin's disease. Whereas murine IL-9 can function on human cells, human IL-9 is inactive on mouse cells. Recombinant murine IL-9 is a 14.3 kDa protein of 127 amino acid residues including 10 cysteine residues which are fully conserved between the human murine proteins.

Recombinant Murine IL-10 Protein

PROTP18893-1 10ug
EUR 380.4
Description: IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNFα. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 active on murine cells, but murine IL-10 is inactive on human cells. Recombinant murine IL-10 is an 18.7 kDa protein of 161 amino acid residues.

Recombinant Rat IL-4 Protein

PROTP20096-1 20ug
EUR 380.4
Description: IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant rat IL-4 is a 14.0 kDa globular protein containing 126 amino acid residues.

Recombinant Murine IL-13 Protein

PROTP20109-1 10ug
EUR 380.4
Description: IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 is cross-species reactive. Recombinant murine IL-13 is a 12.3 kDa protein consisting of 111 amino acid residues.

Recombinant Rat IL-6 Protein

PROTP20607-1 10ug
EUR 380.4
Description: IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant rat IL-6 is a 21.7 kDa protein containing 187 amino acid residues.

Recombinant Rat IL-10 Protein

PROTP29456-1 10ug
EUR 380.4
Description: IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNFα. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 active on murine cells, but murine IL-10 is inactive on human cells. Recombinant rat IL-10 is an 18.7 kDa protein of 160 amino acid residues.

Recombinant Murine IL-11 Protein

PROTP47873-1 10ug
EUR 380.4
Description: IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury. Recombinant Murine IL-11 is a 19.1 kDa protein consisting of 179 amino acid residues.

Recombinant Rat IL-7 Protein

PROTP56478-1 10ug
EUR 380.4
Description: IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant rat IL-7 is a 15.0 kDa protein containing 130 amino acid residues.

Recombinant Rat IL-15 Protein

PROTP97604-1 10ug
EUR 380.4
Description: IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant rat IL-15 is a 13.5 kDa protein consisting of 115 amino acid residues.

Recombinant Rat IL-9 Protein

PROTD4A8I9-1 10ug
EUR 380.4
Description: IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes. IL-9 enhances the proliferation of T lymphocytes, mast cells, erthroid precursor cells and megakaryoblastic leukemia cell lines. Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin’s disease. Recombinant rat IL-9 is a 14.3 kDa protein of 127 amino acid residues including 10 cysteine residues which are fully conserved between the human murine proteins.

Recombinant Murine IL-5 Protein

PROTP04401-1 25ug
EUR 380.4
Description: IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant murine IL-5 is a 26.2 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.

Chicken IL-10 Recombinant Protein

R00021-1 5ug/vial
EUR 310.8
Description: IL-10 is an anti-inflammatory cytokine and a member of the IL-10 family of cytokines, which have indispensable functions in many infectious and inflammatory diseases. Chicken IL-10 Recombinant Protein is purified interleukin-10 produced in yeast.

Canine IL-13 Recombinant Protein

R00077-1 5ug/vial
EUR 310.8
Description: IL-13 is an important mediator of allergic inflammation and disease. In addition to effects on immune cells, IL-13 is implicated as a central mediator of the physiologic changes induced by allergic inflammation in many tissues. Canine IL-13 Recombinant Protein is purified interleukin-13 produced in yeast.

Canine IL-6 Recombinant Protein

R00102-1 5ug/vial
EUR 310.8
Description: Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. Canine IL-6 Recombinant Protein is purified interleukin-6 produced in yeast.

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