Thioredoxin-Associated TransmembraneProteins: TMX1 and Little Brothers TMX2, TMX3, TMX4 and TMX5
The endoplasmic reticulum (ER) is web site of synthesis and maturation of membrane and secretory proteins in eukaryotic cells. The ER comprises greater than 20 members of the Protein Disulfide Isomerase (PDI) household.
These enzymes regulate formation, isomerization and disassembly of covalent bonds between cysteine residues. As such, PDIs guarantee protein folding, which is required to achieve purposeful and transport-competent construction, and protein unfolding, which facilitates dislocation of faulty gene merchandise throughout the ER membrane for ER-associated degradation (ERAD). The PDI household contains over a dozen of soluble members and few membrane-bound ones. Amongst these latter, there are 5 PDIs grouped within the thioredoxin-related transmembrane (TMX) protein household.
On this evaluation, we summarize the present data on TMX1, TMX2, TMX3, TMX4 and TMX5, their structural options, regulation and roles in biogenesis and management of the mammalian cell’s proteome.
Ectopic Expression of a Transmembrane Protein KaCyt b 6 from a Crimson Seaweed Kappaphycus alvarezii in Transgenic Tobacco Augmented the Photosynthesis and Progress
Cytochrome b6f complicated is a thylakoid membrane-localized protein and catalyses the switch of electrons from plastoquinol to plastocyanin in photosynthetic electron transport chain. Within the current research, Cytochrome b6 (KaCyt b6) gene from Kappaphycus alvarezii (a purple seaweed) was overexpressed in tobacco. A 935 base pair (bp) lengthy KaCyt b6 cDNA contained an open studying body of 648 bp encoding a protein of 215 amino acids with an anticipated isoelectric level of 8.67 and a molecular mass of 24.37 kDa. The KaCyt b6 gene was overexpressed in tobacco beneath management of CaMV35S promoter.
The transgenic tobacco had greater electron switch fee and photosynthetic yield over wild-type and vector management tobacco. The KaCyt b6 tobacco additionally exhibited considerably greater photosynthetic fuel trade (PN) and improved water use effectivity.
The transgenic crops had greater ratio of PN and intercellular CO2. The KaCyt b6 transgenic tobacco confirmed greater estimates of photosystem II quantum yield, greater exercise of the water-splitting complicated, PSII photochemistry, and photochemical quenching. The basal quantum yield of nonphotochemical processes in PSII was recorded decrease in KaCyt b6 tobacco. Transgenic tobacco contained greater contents of carotenoids and complete chlorophyll and likewise had higher ratios of chlorophyll a and b, and carotenoids and complete chlorophyll contents therefore improved photosynthetic effectivity and manufacturing of sugar and starch.
The KaCyt b6 transgenic crops carried out superior beneath management and greenhouse circumstances. To one of the best of our data by way of literature survey, that is the primary report on characterization of KaCyt b6 gene from Okay. alvarezii for enhanced photosynthetic effectivity and progress in tobacco.
Description: Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. Swine IL-6 Recombinant Protein is purified interleukin-6 produced in yeast.
Description: IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. Swine IL-4 Recombinant Protein is purified interleukin-4 produced in yeast.
Description: Interleukin-2 (IL-2) is a cytokine produced by T-helper cells in response to antigenic or mitogenic stimulation. It is required for T-cell proliferation and other activities crucial to the regulation of the immune response. Rabbit IL-2 Recombinant Protein is purified interleukin-2 produced in yeast.
Description: IL-17A is a member of the IL-17 family of cytokines, whose members are involved in numerous immune regulatory functions. IL-17 induces the production of many other cytokines, chemokines, and prostaglandins. Swine IL-17A Recombinant Protein is purified interleukin-17A produced in yeast.
Description: IL-1 beta (IL-1β) is a member of the interleukin 1 family of cytokines. The IL-1 beta cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Ovine IL-1 beta Recombinant Protein is purified interleukin-1 beta cytokine produced in yeast.
Description: Quantitative sandwich ELISA kit for measuring Human Interleukin 8, IL-8 in samples from serum, cell culture supernates, saliva, urine, cerebrospinalfluid (CSF), tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitative sandwich ELISA kit for measuring Human Interleukin 8, IL-8 in samples from serum, cell culture supernates, saliva, urine, cerebrospinalfluid(CSF), tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Interleukin 8,IL-8 in samples from serum, plasma, tissue homogenates and other biological fluids.
Human Interleukin-8 (IL-8) Antibody (Biotin Conjugate)
Gentaur's IL-8 CLIA kit utilizes the Sandwich- CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Human IL-8 . Standards or samples are added to the micro CLIA plate wells and combined with the
Gentaur's IL-8 ELISA kit utilizes the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human IL-8. Standards or samples are added to the micro ELISA plate wells and combined with th
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human IL-8 . This antibody is tested and proven to work in the following applications:
Immunogen information: Synthesized peptide derived from the C-terminal region of human IL-8
Applications tips:
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human IL-8
Immunogen information: Synthesized peptide derived from the C-terminal region of human IL-8
Applications tips:
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human IL-8
Immunogen information: Synthesized peptide derived from the C-terminal region of human IL-8
Applications tips:
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human IL-8
Immunogen information: Synthesized peptide derived from the Internal region of human IL-8
Applications tips:
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IL-8
Immunogen information: Synthesized peptide derived from the Internal region of human IL-8
Applications tips:
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IL-8
Immunogen information: Synthesized peptide derived from the Internal region of human IL-8
Applications tips:
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IL-8
Immunogen information: Synthesized peptide derived from the Internal region of human IL-8
Applications tips:
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IL-8
Immunogen information: Synthesized peptide derived from the Internal region of human IL-8
Applications tips:
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IL-8
Immunogen information: Synthesized peptide derived from the Internal region of human IL-8
Applications tips:
Description: A polyclonal antibody for detection of IL-8 from Human. This IL-8 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IL-8
The protein encoded by IL-8 gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a po
Description: Quantitative sandwich ELISA for measuring Human IL-8 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
The protein encoded by IL-8 gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a po
Description: Quantitative sandwich ELISA for measuring Human IL-8 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
The protein encoded by IL-8 gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a po
Description: Quantitative sandwich ELISA for measuring Human IL-8 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
Description: Interleukin-8 (IL-8) is a proinflammatory CXC chemokine produced by macrophages, epithelial cells. IL-8 is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies
Description: Interleukin-8 (IL-8) is a proinflammatory CXC chemokine produced by macrophages, epithelial cells. IL-8 is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies
Description: Description of target: Interleukin-8, also called neutrophil-activating peptide-1 or SCYB8, is a tissue-derived peptide secreted by several types of cells in response to inflammatory stimuli. Monocyte-derived neutrophil chemotactic factor (MDNCF/IL-8, suggested gene symbol IL8) is a cytokine that chemoattracts and activates neutrophils.1 IL-8 is produced and released from human adipose tissue and from isolated adipocytes in vitro, which may indicate that IL-8 from adipose tissue could be involved in some of the obesity-related complications.2 The MDNCF/IL-8 gene is placed on the human gene map at position 4q12-q21. This is the same location where at least three other members (platelet factor 4, melanoma growth stimulatory activity, and interferon-gamma induced factor) of the platelet factor 4 gene superfamily reside.1 Human IL-8 consists of 99 amino acids in precursor form and 79 amino acids in mature form.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 1 pg/ml
Description: Quantitativesandwich ELISA kit for measuring Rabbit Interleukin 8, IL-8 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitativesandwich ELISA kit for measuring Rabbit Interleukin 8, IL-8 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: Quantitativesandwich ELISA kit for measuring Monkey Interleukin-8, IL-8 in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitativesandwich ELISA kit for measuring Monkey Interleukin-8, IL-8 in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: Quantitative sandwich ELISA kit for measuring Dog Interleukin-8, IL-8 in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
The Transmembrane Proteins M6 and Anakonda Cooperate to Provoke Tricellular Junction Meeting in Epithelia of Drosophila
Cell vertices in epithelia comprise specialised tricellular junctions (TCJs) that seal the paracellular area between three adjoining cells [1, 2]. Though TCJs play basic roles in tissue homeostasis, pathogen protection, and in sensing pressure and cell form [3-5], how they’re assembled, maintained, and transformed is poorly understood. In Drosophila, the transmembrane proteins Anakonda (Aka [6]) and Gliotactin (Gli [7]) are TCJ elements important for epithelial barrier formation.
Moreover, the conserved four-transmembrane-domain protein M6, the one myelin proteolipid protein (PLP) member of the family in Drosophila, localizes to TCJs [8, 9]. PLPs affiliate with cholesterol-rich membrane domains and induce filopodia formation [10, 11] and membrane curvature [12], and Drosophila M6 acts as a tumor suppressor [8], however its function in TCJ formation remained unknown.
Right here, we present that M6 is crucial for the meeting of tricellular, however not bicellular, occluding junctions, and for barrier perform in embryonic epithelia. M6 and Aka localize to TCJs in a mutually dependent method and are collectively required for TCJ localization of Gli, whereas Aka and M6 localize to TCJs independently of Gli. Aka acts instructively and is adequate to direct M6 to cell vertices within the absence of septate junctions, whereas M6 is required permissively to take care of Aka at TCJs.
Moreover, M6 and Aka are mutually dependent for his or her accumulation in a low-mobility pool at TCJs. These findings counsel a hierarchical mannequin for TCJ meeting, the place Aka and M6 promote TCJ formation by way of synergistic interactions that demarcate a definite plasma membrane microdomain at cell vertices.
Immunogen information: Synthesized peptide derived from the C-terminal region of human Dkk-1
Applications tips:
Description: A polyclonal antibody for detection of Dkk-1 from Human, Mouse, Rat. This Dkk-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Dkk-1
Immunogen information: Synthesized peptide derived from the C-terminal region of human Dkk-1
Applications tips:
Description: A polyclonal antibody for detection of Dkk-1 from Human, Mouse, Rat. This Dkk-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Dkk-1
Immunogen information: Synthesized peptide derived from the C-terminal region of human Dkk-1
Applications tips:
Description: A polyclonal antibody for detection of Dkk-1 from Human, Mouse, Rat. This Dkk-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Dkk-1
Description: Enzyme-linked immunosorbent assay kit for quantification of Human DKK-1 in samples from serum, plasma, tissue homogenates and other biological fluids.
Description: Enzyme-linked immunosorbent assay kit for quantification of Rat DKK-1 in samples from serum, plasma, tissue homogenates and other biological fluids.
Alias: DKK1/dickkopf(Xenopus laevis) homolog 1/dickkopf homolog 1(Xenopus laevis)/dickkopf related protein-1/Dickkopf-1/dickkopf-related protein 1/Dkk-1/DKK-1/SKdickkopf-1 like
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml
Description: Description of target: This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.;Species reactivity: Human;Application: ELISA;Assay info: Quantitative Colorimentric Sandwich ELISA;Sensitivity: 63 pg/mL
Immunogen information: Synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160
Applications tips:
Description: A polyclonal antibody for detection of Dkk-3 from Human, Mouse. This Dkk-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160
Immunogen information: Synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160
Applications tips:
Description: A polyclonal antibody for detection of Dkk-3 from Human, Mouse. This Dkk-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160
Immunogen information: Synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160
Applications tips:
Description: A polyclonal antibody for detection of Dkk-3 from Human, Mouse. This Dkk-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160
Description: Description of target: Dickkopf-related protein 3 is a protein that in humans is encoded by the DKK3 gene. This gene encodes a protein that is a member of the dickkopf family. It is mapped to 11p15.3. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Members of the Dkk-related family display unique patterns of mRNA expression in human and mouse tissues, and are secreted when expressed in 293T cells. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL
Description: Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium and have a key role in vascular homeostasis.
Description: Basic natriuretic peptide (BNP), now known as B-type natriuretic peptide (also BNP) or GC-B, is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes).
Description: Insulin-like growth factor I (IGF-1) is a polypeptide endocrine hormone structurally similar to insulin and is mainly produced in the liver when stimulated by growth hormone. IGF-1 is a growth factor that stimulates the proliferation of various cell types including muscle, bone, and cartilage tissue
Neuregulin/Heregulin-1? (NRG-1?/HRG-1?), human recombinant protein
Description: Neuregulin (NRG) is a signaling protein for ErbB2/ErbB4 receptor heterodimers on the cardiac muscle cells and plays an important role in heart structure and function through inducing cardiomyocyte differentiation
IL1RL1 Human, Interleukin-1 Receptor Like-1 Human Recombinant Protein, Sf9
Description: IL 1RL1 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (19-328 a.a.) and fused to an 8 aa His Tag at C-terminus containing a total of 318 amino acids and having a molecular mass of 36.0kDa.;IL 1RL1 shows multiple bands between 40-57kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.
MMP-1 Matrix Metalloproteinase-1 Human Recombinant Protein
Description: MMP 1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 393 amino acids (100-469a.a) and having a molecular mass of 45kDa. MMP 1 is fused to a 23 amino acid His-tag at N-terminus.
PSG1 Human, Pregnancy Specific Beta-1-Glycoprotein 1 Human Recombinant Protein, Sf9
Description: PSG1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 394 amino acids (35-419a.a.) and having a molecular mass of 44.6kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). PSG1 is expressed with a 6 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques.
Description: Parathyroid hormone (1-34) (human), (C181H291N55O51S2), a peptide with the sequence H2N-SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF-OH, MW= 4117.72.
Description: Apolipoprotein A-1 (ApoA-1) is a glycoprotein produced in the liver and intestine that is the major protein component of high density lipoprotein (HDL) particles. ApoA-1 is involved in the reverse transport of cholesterol from peripheral tissues to the liver for recycling and excretion.
Description: Apolipoprotein A-1 (ApoA-1) is a glycoprotein produced in the liver and intestine that is the major protein component of high density lipoprotein (HDL) particles. ApoA-1 is involved in the reverse transport of cholesterol from peripheral tissues to the liver for recycling and excretion.
Description: The WNT gene family compose of structurally related genes that encode secreted signaling proteins. These proteins have been involved in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis.
Description: Gremlin-1 (isoform-1) belongs to a group of diffusible proteins which bind to ligands of the TGF-β family and regulate their activity by inhibiting their access to signaling receptors. The interplay between TGF-β ligands and their natural antagonists has major biological significance during development processes, in which cellular response can vary considerably depending upon the local concentration of the signaling molecule. Gremlin is highly expressed in the small intestine, fetal brain, and colon and lower expression in brain, prostate, pancreas and skeletal muscle. Gremlin-1 regulates multiple functions in early development by specifically binding to and inhibiting the function of BMP-2, -4, and -7. It also plays a role in carcinogenesis and kidney branching morphogenesis. Recombinant Gremlin-1 is a 18.3 kDa protein containing 160 amino acid residues.
Description: The Human Orosomucoid 1 produced from Human pooled serum has a molecular mass of 21.56kDa (calculated without glycosylation) containing 183 amino acid residues.
Description: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues.
Description: PECAM is transmembrane glycoprotein that belongs to the Ig-related superfamily of adhesion molecules. It is highly expressed at endothelial cell junctions, and also expressed in platelets and in most leukocyte sub-types. The primary function of PECAM-1 is the mediation of leukocyte-endothelial cell adhesion and signal transduction. PECAM-1 has been implicated in the pathogenesis of various inflammation related disorders, including thrombosis, multiple sclerosis (MS), and rheumatoid arthritis. The human PECAM-1 gene codes for a 738 amino acid transmembrane glycoprotein containing a 118 amino acid cytoplasmic domain, a 19 amino acid transmembrane domain, and a 574 amino acid extracellular domain. Recombinant human PECAM-1 is a 572 amino acid glycoprotein comprising the extracellular domain of PECAM-1. Monomeric glycosylated PECAM-1 migrates at an apparent molecular weight of approximately 80.0-95.0 kDa by SDS-PAGE analysis under reducing conditions
Description: Angiopoietin-1 (Ang-1) is a secreted ligand for Tie-2, a tyrosine-kinase receptor expressed primarily on vascular endothelial cells and early hematopoietic cells. Ang-1/ Tie-2 signaling promotes angiogenesis during the development, remodeling, and repair of the vascular system. Transgenic mice lacking expression of either Ang-1 or Tie-2 fail to develop a fully functional cardiovascular system and die before birth. Postnatally, the angiogenic activity of Ang-1/Tie-2 is required during normal tissue repair and remodeling of the female endometrium in the menstrual cycle. Ang-1/Tie-2 signaling appears to be regulated by Angiopoietin-2 (Ang-2), a natural antagonist for Tie-2 that exerts its effects through an internal autocrine loop mechanism. In addition to suppressing endothelial cell activation by inhibiting the expression of adhesion and inflammatory molecules, Ang-1 enhances endothelial cell survival and capillary morphogenesis, and lessens capillary permeability. As such, Ang-1 has a potential to become an effective therapeutic agent for treating various endothelium disorders, including several severe human pulmonary diseases. The efficacy of cell-based Ang-1 gene therapy for acute lung injury (ALI) has recently been studied in a rat model of ALI (1). The results of this study show that such therapy can markedly improve lung condition and suggest that Ang-1 therapy may represent a potential new strategy for the treatment and/or prevention of acute respiratory distress injury (ARDI), a significant cause of morbidity and mortality in critically ill patients. Recombinant human ANG-1, derived from HeLa cells, is a C-terminal histidine tagged glycoprotein which migrates with an apparent molecular mass of 60.0 – 70.0 kDa by SDS-PAGE under reducing conditions. Sequencing analysis shows N-terminal sequences starting with Ser-20 and with Asp-70 of the 498 amino acid precursor protein.
(1-328) RAD51D (1-328 a.a.) Human Recombinant Protein
Description: RAD51D (1-328) Human Recombinant produced in E. coli is. a single polypeptide chain containing 351 amino acids and having a molecular mass of 37.4kDa. RAD51D (1-328) is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
NXPH1 Human, Neurexophilin 1 Human Recombinant Protein, Sf9
Description: NXPH1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 259 amino acids (22-271) and having a molecular mass of 29.7kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).;NXPH1 is fused to 9 amino acid His-Tag at C-terminus and purified by proprietary chromatographic techniques.
by 
Anti-IL-8 antibody 
Anti-IL-8 Antibody 
1730 8 SNAP-SEAL 8 OZ 
mAb mouse anti-human IL-8 
Anti-IL-8 Monoclonal Antibody 
IL-8 
Swine IL-6 Recombinant Protein 
Swine IL-4 Recombinant Protein 
Rabbit IL-2 Recombinant Protein 
Swine IL-17A Recombinant Protein 
Individual Reaction Mix 8 
Rabbit Polyclonal antibody Anti-CRBN  Antibody)
Human Interleukin-8 (IL-8) Antibody 
Ovine IL-1 beta Recombinant Protein 
IL-8/CXCL8, Human 
Human IL-8 Protein 
Human IL-8 Antibody 
Recombinant Human IL-8  antibody)
Anti-bovine IL-8 (CXCL8) antibody 
IL-8 Antibody 
CXCL8/IL-8 
IL-8 Inhibitor )
Bovine(IL-8) 
IL-8, Interleukin-8, monkey  ELISA Kit)
Human IL-8(Interleukin 8) ELISA Kit ELISA Kit)
Human Interleukin 8(IL-8)ELISA Kit  CLIA Kit)
Human Interleukin 8 (IL-8) CLIA Kit 
Human Interleukin 8,IL-8 ELISA KIT 
Human Interleukin 8, IL-8 ELISA KIT  ELISA Kit)
Human Interleukin-8 (IL-8) ELISA Kit  ELISA Kit)
Bovine Cytokines IL-8(Cytokines IL-8) ELISA Kit 
Human IL-8 ELISA Kit 
human IL-8 His tag 
IL-8 ELISA KIT|Human )
rec Endothelial IL-8 (human) )
rec Monocyte IL-8 (human) 
IL-8/CXCL8, 72a.a., Human  ELISA Kit)
IL-8 (Human) ELISA Kit 
Human IL-8 ELISA kit 
Recombinant Human IL-8 Protein )
Guinea pig IL-8(Interleukin 8)  ELISA)
Horse Interleukin 8 (IL-8) ELISA 
IL-8, CXCL8, Interleukin-8, canine 
IL-8, CXCL8, Interleukin-8, porcine )
Recombinant Human Interleukin-8/IL-8 (C-6His) )
Recombinant Human Interleukin-8/IL-8 (Ser28-Ser99) )
Recombinant Human Interleukin-8/IL-8 (Ala23-Ser99)  AssayMax ELISA Kit)
Human Interleukin-8 (IL-8) AssayMax ELISA Kit 
ELISA kit for Human Interleukin 8,IL-8  Antibody (Biotin Conjugate))
Human Interleukin-8 (IL-8) Antibody (Biotin Conjugate) )
CLIA kit for Human IL-8 (Interleukin 8) )
ELISA kit for Human IL-8 (Interleukin 8) , human)
IL-8, CXCL8, Interleukin-8 (72 a.a.), human , human)
IL-8, CXCL8, Interleukin-8 (77 a.a.), human 
Polyclonal IL-8 Antibody 
IL-8 Blocking Peptide 
IL-8 Polyclonal Antibody 
CXCR1/IL-8 RA 
CXCR2/IL-8 RB 
Recombinant Bovine IL-8 
Recombinant Chicken IL-8 
Recombinant Dog IL-8 
Recombinant Pig IL-8 
Recombinant Rabbit IL-8 
Human IL-8 PicoKine ELISA Kit , Human)
IL-8/CXCL8 (CHO-expressed), Human )
Human IL-8 Antibody (Biotin Conjugate) , human recombinant)
IL-8 (77 a.a.), human recombinant , human recombinant)
IL-8 (72 a.a.), human recombinant 
Human IL-8 ELISA antibody pair 
ELISA kit for Human IL-8 
CymaxTM Human IL-8 ELISA Kit )
Human IL-8 ELISA kit (4X96T) 
Human IL-8/CXCL8 ELISA Kit  (OKBB00192))
IL-8 ELISA Kit (Human) (OKBB00192) 
Equine Interleukin 8, IL 8 ELISA Kit 
Mouse Interleukin 8, IL 8 ELISA Kit 
Porcine Interleukin 8, IL 8 ELISA Kit 
Sheep Interleukin-8,IL-8 ELISA Kit  ELISA Kit)
Horse IL-8(Interleukin 8) ELISA Kit  ELISA Kit)
Canine IL-8(Interleukin 8) ELISA Kit  ELISA Kit)
Chicken IL-8(Interleukin 8) ELISA Kit  ELISA Kit)
Bovine IL-8(Interleukin 8) ELISA Kit ELISA Kit)
Mouse interleukin 8(IL-8)ELISA Kit 
Rabbit Interleukin 8,IL-8 ELISA Kit  ELISA Kit)
Rabbit IL-8(Interleukin 8) ELISA Kit  ELISA Kit)
Sheep IL-8(Interleukin 8) ELISA Kit  ELISA Kit)
Porcine IL-8(Interleukin-8) ELISA Kit  ELISA Kit)
Monkey IL-8(Interleukin 8) ELISA Kit  ELISA Kit)
Mouse IL-8(Interleukin 8) ELISA Kit  CLIA Kit)
Mouse Interleukin 8 (IL-8) CLIA Kit 
Rabbit Interleukin 8, IL-8 ELISA Kit 
Monkey Interleukin-8, IL-8 ELISA Kit 
Dog Interleukin-8, IL-8 ELISA Kit 
, Mouse)
)
 ELISA Kit)
 : 96 Wells (OKAG00221))
 (OKBB00603))
 [Fc])
 [His])
 [Strep])
 [His])
 [Fc] [Avi])
 ELISA Kit)
 [His])
 [His])
)
, amide, human)
 Human Plasma)
)
, human)
, human recombinant protein)
 (human))
 (human))
 RAD51D (1-328 a.a.) Human Recombinant Protein)
