December 8, 2023
sysbio

Structural Views on Extracellular Recognition and Conformational Adjustments

Structural Views on Extracellular Recognition and Conformational Adjustments of A number of Kind-I Transmembrane Receptors

Kind-I transmembrane proteins characterize a big group of 1,412 proteins in people with a mess of features in cells and tissues. They’re characterised by an extracellular, or luminal, N-terminus adopted by a single transmembrane helix and a cytosolic C-terminus.

The area composition and buildings of the extracellular and intercellular segments differ considerably amongst its members. A lot of the type-I transmembrane proteins have roles in cell signaling processes, as ligands or receptors, and in mobile adhesion. The extracellular section usually determines specificity and may management signaling and adhesion.

Right here we concentrate on latest structural understanding on how the extracellular segments of a number of numerous type-I transmembrane proteins have interaction in interactions and may endure conformational modifications for his or her perform. Interactions on the extracellular aspect by proteins on the identical cell or between cells are enhanced by the transmembrane setting. Extracellular conformational area rearrangement and structural modifications inside domains alter the properties of the proteins and are used to manage signaling occasions.

The mixture of structural properties and interactions can help the formation of larger-order assemblies on the membrane floor which are necessary for mobile adhesion and intercellular signaling.

MicroRNA-548ac induces apoptosis in laryngeal squamous cell carcinoma cells by concentrating on transmembrane protein 158

Laryngeal most cancers is a typical head and neck most cancers that results the standard of lifetime of these affected. Early analysis and remedy are important to attenuate the dangerous results of laryngeal most cancers, which might enhance the survival charge of sufferers following surgical procedure and retain the voice perform of the larynx.

The aim of the current examine was to discover the molecular mechanism of the event of laryngeal most cancers and to find out the biomarker for the analysis and remedy of laryngeal most cancers. Reverse transcription-quantitative PCR (RT-qPCR) and The Most cancers Genome Atlas database evaluation had been used to substantiate excessive expression of TMEM158 in laryngeal most cancers.

The consequences of TMEM158 and miR-548ac was investigated by in vitro and in vivo assays (MTT assay, colony-formation assay, movement cytometry assay, western blotting and tumor xenograft assay). Luciferase reporter assay, western blotting and RTq-PCR had been used to substantiate that miR-548 immediately focused the three’-untranslated area of TMEM158 and inhibited TMEM158 expression.

Taken collectively, the current outcomes counsel that miR-548ac features as an important most cancers suppressor in laryngeal most cancers, which induces apoptosis in laryngeal most cancers cells by suppressing TMEM158. Thus, miR-548ac could also be a possible goal for the remedy of laryngeal most cancers.

sysbio
sysbio

Tie-2 Antibody

45046-100ul 100ul
EUR 302.4

Tie-2 Antibody

45046-50ul 50ul
EUR 224.4

Tie-2/ Rat Tie- 2 ELISA Kit

ELA-E0126r 96 Tests
EUR 1063.2

Rabbit Anti-human TIE-2 antiserum #2

TIE22-S 100 ul
EUR 548.4

Recombinant Mouse TIE-2-Fc chimeric protein

TIE26-R-100 100 ug
EUR 1074

Recombinant Mouse TIE-2-Fc chimeric protein

TIE26-R-20 20 ug
EUR 343.2

Tie- 2 Antibody

ABD7500 100 ug
EUR 525.6

Recombinant (CHO cells) Mouse TIE-2 Fc Chimera

RP-706 10 ug
EUR 343.2

Rabbit Anti-human TIE-1 antiserum #2

TIE12-S 100 ul
EUR 548.4

Tie-2 Conjugated Antibody

C45046 100ul
EUR 476.4

Tie-2 Polyclonal Antibody

ABP56367-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Tie-2 from Human, Mouse. This Tie-2 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the non-phosphorylation site of Y1102

Tie-2 Polyclonal Antibody

ABP56367-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Tie-2 from Human, Mouse. This Tie-2 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the non-phosphorylation site of Y1102

Tie-2 Polyclonal Antibody

ABP56367-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Tie-2 from Human, Mouse. This Tie-2 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the non-phosphorylation site of Y1102

Tie-2 Polyclonal Antibody

ABP56368-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Tie-2 from Human, Mouse. This Tie-2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the non-phosphorylation site of Y992

Tie-2 Polyclonal Antibody

ABP56368-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Tie-2 from Human, Mouse. This Tie-2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the non-phosphorylation site of Y992

Tie-2 Polyclonal Antibody

ABP56368-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Tie-2 from Human, Mouse. This Tie-2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the non-phosphorylation site of Y992

Tie-2 Polyclonal Antibody

ES7366-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against Tie-2 from Human/Mouse. This antibody is tested and validated for IHC, WB, ELISA, WB, ELISA

Tie-2 Polyclonal Antibody

ES7366-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against Tie-2 from Human/Mouse. This antibody is tested and validated for IHC, WB, ELISA, WB, ELISA

Tie-2 Polyclonal Antibody

ES7367-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against Tie-2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Tie-2 Polyclonal Antibody

ES7367-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against Tie-2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Recombinant Mouse TIE-1 Fc Chimera

7-04186 1µg Ask for price

Recombinant Mouse TIE-1 Fc Chimera

7-04187 3µg Ask for price

Recombinant Mouse TIE-1 Fc Chimera

7-04188 100µg Ask for price

Rabbit Anti-human TIE-2 IgG #2, aff pure

TIE22-A 100 ug
EUR 578.4

Anti-Tie-2 antibody

STJ96015 200 µl
EUR 236.4
Description: Rabbit polyclonal to Tie-2.

Anti-Tie-2 antibody

STJ96016 200 µl
EUR 236.4
Description: Rabbit polyclonal to Tie-2.

Tie-2 Blocking Peptide

DF7500-BP 1mg
EUR 234

Purified Mouse TIE-2 (1-744aa) recombinant control protein for WB

TIE24-C 100 ul
EUR 343.2

Rabbit Anti-human TIE-1 IgG #2, aff pure

TIE12-A 100 ug
EUR 578.4

Rabbit Anti-human TIE-2 IgG #1 aff pure

TIE21-A 100 ug
EUR 578.4

Monoclonal Anti-human TIE-2 IgG # 3, aff pure

TIE23-M 100 ug
EUR 578.4

TIE-1 Antibody

47997-100ul 100ul
EUR 399.6

TIE-1 Antibody

47997-50ul 50ul
EUR 286.8

Recombinant (CHO cells) Mouse TIE-1 Fc Chimera

RP-704 10 ug
EUR 343.2

Tie-2 (phospho Tyr992) Polyclonal Antibody

ABP53387-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Tie-2 phospho Tyr992) from Human, Mouse. This Tie-2 phospho Tyr992) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the phosphorylation site of Y992

Tie-2 (phospho Tyr992) Polyclonal Antibody

ABP53387-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Tie-2 phospho Tyr992) from Human, Mouse. This Tie-2 phospho Tyr992) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the phosphorylation site of Y992

Tie-2 (phospho Tyr992) Polyclonal Antibody

ABP53387-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Tie-2 phospho Tyr992) from Human, Mouse. This Tie-2 phospho Tyr992) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the phosphorylation site of Y992

Tie-2 (phospho Tyr992) Polyclonal Antibody

ES4386-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against Tie-2 (phospho Tyr992) from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Tie-2 (phospho Tyr992) Polyclonal Antibody

ES4386-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against Tie-2 (phospho Tyr992) from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Tie-2 (phospho Tyr1108) Polyclonal Antibody

ABP56365-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Tie-2 phospho Tyr1108) from Human, Mouse. This Tie-2 phospho Tyr1108) antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the phosphorylation site of Y1108

Tie-2 (phospho Tyr1108) Polyclonal Antibody

ABP56365-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Tie-2 phospho Tyr1108) from Human, Mouse. This Tie-2 phospho Tyr1108) antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the phosphorylation site of Y1108

Tie-2 (phospho Tyr1108) Polyclonal Antibody

ABP56365-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Tie-2 phospho Tyr1108) from Human, Mouse. This Tie-2 phospho Tyr1108) antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the phosphorylation site of Y1108

Tie-2 (phospho Tyr1102) Polyclonal Antibody

ABP56366-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Tie-2 phospho Tyr1102) from Human, Mouse. This Tie-2 phospho Tyr1102) antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the phosphorylation site of Y1102

Tie-2 (phospho Tyr1102) Polyclonal Antibody

ABP56366-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Tie-2 phospho Tyr1102) from Human, Mouse. This Tie-2 phospho Tyr1102) antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the phosphorylation site of Y1102

Tie-2 (phospho Tyr1102) Polyclonal Antibody

ABP56366-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Tie-2 phospho Tyr1102) from Human, Mouse. This Tie-2 phospho Tyr1102) antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the phosphorylation site of Y1102

Tie-2 (phospho Tyr1108) Polyclonal Antibody

ES7364-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against Tie-2 (phospho Tyr1108) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

Tie-2 (phospho Tyr1108) Polyclonal Antibody

ES7364-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against Tie-2 (phospho Tyr1108) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

Tie-2 (phospho Tyr1102) Polyclonal Antibody

ES7365-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against Tie-2 (phospho Tyr1102) from Human/Mouse. This antibody is tested and validated for IHC, WB, ELISA

Tie-2 (phospho Tyr1102) Polyclonal Antibody

ES7365-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against Tie-2 (phospho Tyr1102) from Human/Mouse. This antibody is tested and validated for IHC, WB, ELISA

TIE-2/CD202b Fc Chimera

PR27152 2 ug
EUR 229.2

Mouse Tie1/ Tyrosine-protein kinase receptor Tie-1 ELISA Kit

E1470Mo 1 Kit
EUR 675.6

Mouse Tie1(Tyrosine-protein kinase receptor Tie-1) ELISA Kit

EM0304 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml

TIE-1 Conjugated Antibody

C47997 100ul
EUR 476.4

Tie-1 Polyclonal Antibody

ABP56395-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Tie-1 from Human, Mouse, Rat. This Tie-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Tie-1 at AA range: 820-900

Tie-1 Polyclonal Antibody

ABP56395-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Tie-1 from Human, Mouse, Rat. This Tie-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Tie-1 at AA range: 820-900

Tie-1 Polyclonal Antibody

ABP56395-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Tie-1 from Human, Mouse, Rat. This Tie-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Tie-1 at AA range: 820-900

Tie-1 Polyclonal Antibody

ES7394-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against Tie-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

Tie-1 Polyclonal Antibody

ES7394-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against Tie-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

TEK/Tie-2 ELISA KIT|Human

EF007833 96 Tests
EUR 826.8

Human TIE-2 Control/blocking peptide #2

TIE22-P 100 ug
EUR 196.8

Mouse Tyrosine-Protein Kinase Receptor Tie-1 (TIE1) ELISA Kit

abx254664-96tests 96 tests
EUR 848.4

Mouse Tyrosine-Protein Kinase Receptor Tie-1 (TIE1) ELISA Kit

20-abx154761
  • EUR 7970.40
  • EUR 4250.40
  • EUR 990.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Tyrosine-Protein Kinase Receptor Tie-1 (TIE1) ELISA Kit

abx573285-96tests 96 tests
EUR 848.4

Recombinant Human TIE-2 Fc Chimera

7-04189 1µg Ask for price

Recombinant Human TIE-2 Fc Chimera

7-04190 3µg Ask for price

Recombinant Human TIE-2 Fc Chimera

7-04191 100µg Ask for price

TIE-2 Fc Chimera Protein (Recombinant)

20-abx073609
  • EUR 393.60
  • EUR 5672.40
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

TIE-2 Fc Chimera Protein (Recombinant)

20-abx073610
  • EUR 393.60
  • EUR 5672.40
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Anti-Phospho-Tie-2 (Y992) antibody

STJ90597 200 µl
EUR 236.4
Description: Rabbit polyclonal to Phospho-Tie-2 (Y992).

Anti-Phospho-Tie-2 (Y1108) antibody

STJ90693 200 µl
EUR 236.4
Description: Rabbit polyclonal to Phospho-Tie-2 (Y1108).

Anti-Phospho-Tie-2 (Y1102) antibody

STJ91136 200 µl
EUR 236.4
Description: Rabbit polyclonal to Phospho-Tie-2 (Y1102).

Tie1 ELISA Kit| Mouse Tyrosine-protein kinase receptor Tie-1 ELI

EF012984 96 Tests
EUR 826.8

Mouse tyrosine kinase with immunoglobulin-like and EGF-like domains 2(Tie-2)ELISA Kit

GA-E0224MS-48T 48T
EUR 403.2

Mouse tyrosine kinase with immunoglobulin-like and EGF-like domains 2(Tie-2)ELISA Kit

GA-E0224MS-96T 96T
EUR 640.8

Mouse tyrosine kinase with immunoglobulin-like and EGF-like domains 2(Tie-2)ELISA Kit

QY-E21557 96T
EUR 433.2

Mouse tyrosine kinase with immunoglobulin-like and EGF-like domains 2,Tie-2 ELISA kit

YLA0716MO-48T 48T
EUR 465

Mouse tyrosine kinase with immunoglobulin-like and EGF-like domains 2,Tie-2 ELISA kit

YLA0716MO-96T 96T
EUR 600

Rabbit Anti-human TIE-1 IgG #1, aff pure

TIE11-A 100 ug
EUR 578.4

Nori® Rat Tie-2 ELISA Kit

GR118394 96-well
EUR 461

Nori® Human Tie-2 ELISA Kit

GR106458 96-well
EUR 461

Nori® Zebrafish Tie-2 ELISA Kit

GR206183 96-well
EUR 461

Recombinant (Sf9) Human TIE-2 Fc Chimera

RP-705 10 ug
EUR 343.2

Human TIE-1 Control/blocking peptide #2

TIE12-P 100 ug
EUR 196.8

Human TIE-2 Control/blocking peptide #1

TIE21-P 100 ug
EUR 196.8

TIE-1 Fc Chimera

PR27153 2 ug
EUR 229.2

Anti-Tie-1 antibody

STJ96014 200 µl
EUR 236.4
Description: Rabbit polyclonal to Tie-1.

Recombinant Human TIE-2-FC chimeric protein

TIE25-R-20 20 ug
EUR 343.2

Nori® Human Tie-2 ELISA Kit (2 plates)

GR106458-2 2 x 96-well
EUR 832

Polyclonal TIE1 / TIE Antibody (C-Terminus)

APR02742G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TIE1 / TIE (C-Terminus). This antibody is tested and proven to work in the following applications:

Tie-1 Recombinant Protein

91-454 0.05 mg
EUR 405.6
Description: TIE-1 (Tyrosine Kinase with Ig and EGF Homology domains 1) and TIE-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily. These receptors are expressed on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis. Human TIE-1 cDNA encodes a 1124 amino acid (aa) residue precursor protein with an 18aa signal peptide, a 727 aa extracellular domain and a 354 aa cytoplasmic domain. so far, two ligands have been described for TIE-2 [angiopoietin-1 (Ang1) and angiopoietin-2 (Ang2)], but no ligand was found for TIE-1.

Polyclonal TIE Antibody (N-term)

APR05992G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TIE (N-term). This antibody is tested and proven to work in the following applications:

Tie-2 ELISA Kit (Human) : 96 Wells (OKAG00257)

OKAG00257 96 Wells
EUR 715.2
Description: Description of target: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.;Species reactivity: Human;Application: ELISA;Assay info: Quantitative Colorimentric Sandwich ELISA;Sensitivity: 157 pg/mL

Human TEK/Tie-2(Angiopoietin Receptor Tie2) ELISA Kit

EH0293 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Recombinant Human Tyrosine-Protein Kinase Receptor Tie-1/Tie-1 (C-6His)

C502-10ug 10ug
EUR 108
Description: Lyophilized from a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.

Recombinant Human Tyrosine-Protein Kinase Receptor Tie-1/Tie-1 (C-6His)

C502-1mg 1mg
EUR 1399.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.

Recombinant Human Tyrosine-Protein Kinase Receptor Tie-1/Tie-1 (C-6His)

C502-500ug 500ug
EUR 997.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.

Recombinant Human Tyrosine-Protein Kinase Receptor Tie-1/Tie-1 (C-6His)

C502-50ug 50ug
EUR 205.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.

Recombinant Human TIE-1 Fc Chimera

7-04183 1µg Ask for price

Recombinant Human TIE-1 Fc Chimera

7-04184 3µg Ask for price

Recombinant Human TIE-1 Fc Chimera

7-04185 100µg Ask for price

TIE-1 Fc Chimera Protein (Recombinant)

20-abx073607
  • EUR 393.60
  • EUR 5672.40
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

TIE-1 Fc Chimera Protein (Recombinant)

20-abx073608
  • EUR 393.60
  • EUR 5672.40
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Purified Human TIE-2 (1-744aa) recombinant control protein for WB

TIE22-C 100 ul
EUR 343.2

Mouse tyrosine kinase with immunoglobulin-like and EGF-like domains 1, Tie-1 ELISA kit

CSB-E07391m-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Mouse tyrosine kinase with immunoglobulin-like and EGF-like domains 1, Tie-1 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse tyrosine kinase with immunoglobulin-like and EGF-like domains 1, Tie-1 ELISA kit

1-CSB-E07391m
  • EUR 1135.20
  • EUR 6938.40
  • EUR 3672.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse tyrosine kinase with immunoglobulin-like and EGF-like domains 1, Tie-1 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Bag/Cable Tie Pvc White 200X4.8

BAG1152 PK100
EUR 4.07

Recombinant (Sf9) Human TIE-1 Fc Chimera

RP-703 10 ug
EUR 343.2

TIE-2 ELISA Kit| Rat Tyrosine Kinase With Immunoglobulin-Like An

EF018077 96 Tests
EUR 826.8

Recombinant Human TIE-1 (~740aa)-Fc Protein Control

TIE15-R-100 100 ug
EUR 1074

Recombinant Human TIE-1 (~740aa)-Fc Protein Control

TIE15-R-20 20 ug
EUR 343.2

Tie-1 ELISA Kit (Human) : 96 Wells (OKAG00256)

OKAG00256 96 Wells
EUR 715.2
Description: Description of target: This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.;Species reactivity: Human;Application: ELISA;Assay info: Quantitative Colorimentric Sandwich ELISA;Sensitivity: 157 pg/mL

Rat Tyrosine Kinase With Immunoglobulin-Like And EGF-Like Domains 2 (TIE-2) CLIA Kit

abx197868-96tests 96 tests
EUR 990

Rat TIE-2(Tyrosine Kinase With Immunoglobulin-Like And EGF-Like Domains 2) ELISA Kit

ER1383 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.188 ng/ml

Rat tyrosine kinase with immunoglobulin-like and EGF-like domains 2(Tie-2)ELISA Kit

GA-E0294RT-48T 48T
EUR 380.4

Rat tyrosine kinase with immunoglobulin-like and EGF-like domains 2(Tie-2)ELISA Kit

GA-E0294RT-96T 96T
EUR 595.2

Rat tyrosine kinase with immunoglobulin-like and EGF-like domains 2(Tie-2)ELISA Kit

QY-E11358 96T
EUR 433.2

Rat tyrosine kinase with immunoglobulin-like and EGF-like domains 2,Tie-2 ELISA kit

YLA0893RA-48T 48T
EUR 465

Rat tyrosine kinase with immunoglobulin-like and EGF-like domains 2,Tie-2 ELISA kit

YLA0893RA-96T 96T
EUR 600

Cow Tyrosine-Protein Kinase Receptor Tie-1 (TIE1) ELISA Kit

abx575401-96tests 96 tests
EUR 1093.2

Pig Tyrosine-Protein Kinase Receptor Tie-1 (TIE1) ELISA Kit

abx360765-96tests 96 tests
EUR 990

Human tyrosine kinase with immunoglobulin-like and EGF-like domains 2,Tie-2 ELISA Kit

201-12-1220 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human tyrosine kinase with immunoglobulin-like and EGF-like domains 2(Tie-2)ELISA Kit

GA-E1236HM-48T 48T
EUR 346.8

Human tyrosine kinase with immunoglobulin-like and EGF-like domains 2(Tie-2)ELISA Kit

GA-E1236HM-96T 96T
EUR 559.2

Human tyrosine kinase with immunoglobulin-like and EGF-like domains 2(Tie-2)ELISA Kit

QY-E00695 96T
EUR 433.2

Human tyrosine kinase with immunoglobulin-like and EGF-like domains 2,Tie-2 ELISA Kit

YLA1748HU-48T 48T
EUR 435

Human tyrosine kinase with immunoglobulin-like and EGF-like domains 2,Tie-2 ELISA Kit

YLA1748HU-96T 96T
EUR 562.5

Bovine tyrosine kinase with immunoglobulin-like and EGF-like domains 2,Tie-2 ELISA kit

YLA0149BO-48T 48T
EUR 502.5

Bovine tyrosine kinase with immunoglobulin-like and EGF-like domains 2,Tie-2 ELISA kit

YLA0149BO-96T 96T
EUR 618.75

Human Tyrosine-Protein Kinase Receptor Tie-1 (TIE1) ELISA Kit

abx253484-96tests 96 tests
EUR 848.4

Human Tyrosine-Protein Kinase Receptor Tie-1 (TIE1) ELISA Kit

abx573824-96tests 96 tests
EUR 848.4

Human Tyrosine-Protein Kinase Receptor Tie-1 (TIE1) ELISA Kit

20-abx153296
  • EUR 6373.20
  • EUR 3404.40
  • EUR 801.60
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human TIE1/ Tyrosine-protein kinase receptor Tie-1 ELISA Kit

E2497Hu 1 Kit
EUR 644.4

S-palmitoylation of swine interferon-inducible transmembrane protein is crucial for its anti-JEV exercise

Japanese encephalitis virus (JEV) is an infectious pathogen spreading in a variety of vertebrate species. Pigs are amplifying hosts of JEV and considered maintained in nature predominantly by avian-mosquito cycles. Within the innate immune system,

interferon-inducible transmembrane protein (IFITM) is a small transmembrane protein household and has been recognized as the primary line of protection towards a broad vary of RNA virus invasion. On this paper, we discovered that swine IFITM (sIFITM) might limit the replication of each JEV vaccine pressure and wild pressure NJ-2008. The cysteine S-palmitoylation modification of sIFITM performs necessary roles of their anti-JEV results and intracellular distributions.

Our findings present the anti-JEV actions of swine interferon-inducible transmembrane proteins and broaden the antiviral spectrum of IFITM protein household. The preliminary exploration of S-palmitoylation modification of sIFITM might contribute to understanding of the antiviral molecular mechanism of sIFITM.

Polymersome-based modular nanoreactors with size-selective transmembrane permeability.

Polymersome nanoreactors encapsulating the enzymes or particulate catalysts appeal to curiosity due to their potential use as modular reactors to synthesize advanced compounds by way of a cascade of chemical reactions in a single batch.

To realize these objectives, a key requirement is the tunable permeability of the polymersome membrane, which permits the size-selective transportation of reagents and merchandise whereas defending the encapsulated catalysts throughout the chemical response.

 We report right here a stimuli-responsive route for controlling the permeability of the polymersomes of the binary mix of poly(ethylene glycol)-b-polystyrene (PEG-b-PS) and poly(ethylene glycol)-b-poly(acrylbenzylborate) (PEG-b-PABB). The presence of H2O2 (1 mM) within the medium (0.1M PBS, pH 7.4) triggers the oxidation of benzyl borate pendants of PABB to type poly(acrylic acid) (PAA).

This transformation leads to the perforation of the compartmentalizing membrane of polymersomes by the dissolution of PEG-b-PAA domains embedded within the inert PEG-b-PS matrix. By controlling the composition of the stimuli-responsive block copolymer, the polymersomes of the binary mix exhibit size-selective permeability with out dropping the structural integrity. Launch of fluorescent company with completely different sizes (Fluorescein, PEG2k-Cm, PEG5k-Rho) could be managed by tuning the composition (PEG-b-PS/PEG-b-PABB = 100/0 ~ 80/20) of blended polymersomes.

Selective permeability of the membrane gives safety of the encapsulated enzymes from exterior proteases current within the medium, ensuing within the one-pot synthesis of small molecules by way of cascades of chemical reactions.

The nanoparticular catalysts are additionally encapsulated inside the permeable polymersomes, serving as modular reactors for the conversion of natural compounds by way of a cascade of reactions.

Mouse Anti-Human CD80 mAb

CM015-100ug 100ug
EUR 224.4

Mouse Anti-Human CD80 mAb

CM015-25ug 25ug
EUR 146.4

Mouse Anti Human Cd80 Monoclonal Antibody,RPE-Cy5

CABT-46707MH 2ml
EUR 920.4

Human T- lymphocyte activation antigen CD80, CD80 ELISA KIT

ELI-06511h 96 Tests
EUR 988.8

Anti-Hu CD80 PE

1P-287-T025 25 tests
EUR 168

Anti-Hu CD80 PE

1P-287-T100 100 tests
EUR 288

Anti-Hu CD80 APC

1A-287-T025 25 tests
EUR 168

Anti-Hu CD80 APC

1A-287-T100 100 tests
EUR 288

Anti-Hu CD80 FITC

1F-287-T025 25 tests
EUR 146.4

Anti-Hu CD80 FITC

1F-287-T100 100 tests
EUR 244.8

Anti-Hu CD80 PerCP

PC-287-T025 25 tests
EUR 168

Anti-Hu CD80 PerCP

PC-287-T100 100 tests
EUR 288

Anti-Hu CD80 Purified

11-287-C025 0.025 mg
EUR 124.8

Anti-Hu CD80 Purified

11-287-C100 0.1 mg
EUR 200.4

Anti-Ms CD80 Purified

11-627-C100 0.1 mg
EUR 135.6

Mouse Anti-Human CD80 mAbConjugated Antibody

CCM015 100ul
EUR 476.4

Human CD80 ELISA Kit

ELA-E2026h 96 Tests
EUR 988.8

Human T-lymphocyte activation antigen CD80 / B7-1 (CD80) ELISA Kit

20-abx258485
  • EUR 8534.40
  • EUR 4550.40
  • EUR 1054.80
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human T-lymphocyte activation antigen CD80 / B7-1 (CD80) ELISA Kit

abx250225-96tests 96 tests
EUR 801.6

Human CD80 shRNA Plasmid

20-abx950663
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Human B7-1/CD80

MO15156 100 ug
EUR 700.8

Human B7-1/CD80

GT15255 100 ug
EUR 856.8

CD80 ELISA KIT|Human

EF000069 96 Tests
EUR 826.8

CD80 (Human) ELISA Kit

K4172-100 each
EUR 874.8

Anti-Hu CD80 PE-Cy7

T7-287-T025 25 tests
EUR 184.8

Anti-Hu CD80 PE-Cy7

T7-287-T100 100 tests
EUR 321.6

Anti-Hu CD80 PE-Cy5

T8-287-T025 25 tests
EUR 168

Anti-Hu CD80 PE-Cy5

T8-287-T100 100 tests
EUR 288

Anti-Hu CD80 Pacific Blue

PB-287-T025 25 tests
EUR 184.8

Anti-Hu CD80 Pacific Blue

PB-287-T100 100 tests
EUR 322.8

Anti-Hu CD80 Alexa Fluor700

A7-287-T025 25 tests
EUR 184.8

Anti-Hu CD80 Alexa Fluor700

A7-287-T100 100 tests
EUR 322.8

CD80 Human Recombinant Protein

PROTP33681 Regular: 5ug
EUR 380.4
Description: CD80 Human Recombinant produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 216 amino acids (35-242a.a.) and having a molecular mass of 24.9kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).;CD80 is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

CD80 Recombinant Protein (Human)

RP051190 100 ug Ask for price

Human CellExp? CD80, human recombinant

7383-10 each
EUR 280.8

Human CellExp? CD80, human recombinant

7383-50 each
EUR 810

Mouse Anti-Human CD80, PE Conjugated mAb

CM017-100T 100T
EUR 441.6

Mouse Anti-Human CD80, PE Conjugated mAb

CM017-25T 25T
EUR 224.4

Mouse Anti-Human CD80, FITC Conjugated mAb

CM016-100T 100T
EUR 372

Mouse Anti-Human CD80, FITC Conjugated mAb

CM016-25T 25T
EUR 207.6

Mouse Anti-Human CD80, Biotin Conjugated mAb

CM018-100ug 100ug
EUR 328.8

Mouse Anti-Human CD80, Biotin Conjugated mAb

CM018-25ug 25ug
EUR 181.2

CD80 antibody

10R-1912 100 ul
EUR 483.6
Description: Mouse monoclonal CD80 antibody

CD80 antibody

10R-3627 100 ul
EUR 829.2
Description: Mouse monoclonal CD80 antibody

CD80 antibody

10R-3628 100 ul
EUR 829.2
Description: Mouse monoclonal CD80 antibody

CD80 antibody

10R-3629 100 ul
EUR 829.2
Description: Mouse monoclonal CD80 antibody

CD80 antibody

10R-3630 100 ul
EUR 829.2
Description: Mouse monoclonal CD80 antibody

CD80 antibody

10R-3631 100 ul
EUR 829.2
Description: Mouse monoclonal CD80 antibody

CD80 antibody

10R-3632 100 ul
EUR 829.2
Description: Mouse monoclonal CD80 antibody

CD80 antibody

10R-3634 100 ul
EUR 829.2
Description: Mouse monoclonal CD80 antibody

CD80 antibody

10R-3635 100 ul
EUR 829.2
Description: Mouse monoclonal CD80 antibody

CD80 antibody

10R-6436 100 ug
EUR 282
Description: Armenian Hamster monoclonal CD80 antibody

CD80 antibody

10R-6437 100 ug
EUR 230.4
Description: Mouse monoclonal CD80 antibody

CD80 antibody

10R-6844 100 ul
EUR 829.2
Description: Mouse monoclonal CD80 antibody

CD80 antibody

10R-7741 500 ug
EUR 678
Description: Rat monoclonal CD80 antibody

CD80 antibody

10R-CD80bMS 500 ug
EUR 444
Description: Rat monoclonal CD80 antibody

CD80 Antibody

37436-100ul 100ul
EUR 302.4

CD80 Antibody

8679-002mg 0.02 mg
EUR 206.18
Description: CD80, also known as B7-1, is a type I membrane protein that is a member of the immunoglobulin superfamily. Like the related protein CD86, this protein is expressed by antigen-presenting cells, and is the ligand for two proteins at the cell surface of T cells, CD28 and the cytotoxic T-lymphocyte-associated protein 4 (CTLA-4). Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell and induces T-cell proliferation and cytokine production. CTLA-4 binding negatively regulates T-cell activation and diminishes the immune response (1). Blocking the CTLA-4-CD80/CD86 interaction has been shown to enhance T-cell functions in acute lymphoblastomic leukemia (ALL), suggesting that this pathway may be an attractive target for future cancer immunotherapy (2).

CD80 Antibody

8679-01mg 0.1 mg
EUR 523.7
Description: CD80, also known as B7-1, is a type I membrane protein that is a member of the immunoglobulin superfamily. Like the related protein CD86, this protein is expressed by antigen-presenting cells, and is the ligand for two proteins at the cell surface of T cells, CD28 and the cytotoxic T-lymphocyte-associated protein 4 (CTLA-4). Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell and induces T-cell proliferation and cytokine production. CTLA-4 binding negatively regulates T-cell activation and diminishes the immune response (1). Blocking the CTLA-4-CD80/CD86 interaction has been shown to enhance T-cell functions in acute lymphoblastomic leukemia (ALL), suggesting that this pathway may be an attractive target for future cancer immunotherapy (2).

CD80 Antibody

49409-100ul 100ul
EUR 399.6

CD80 Antibody

49409-50ul 50ul
EUR 286.8

CD80 antibody

70R-13908 100 ug
EUR 386.4
Description: Affinity purified Mouse polyclonal CD80 antibody

CD80 antibody

70R-35657 100 ug
EUR 418.8
Description: Rabbit polyclonal CD80 antibody

CD80 Antibody

ABD7682 100 ug
EUR 525.6

CD80 Antibody

ABD8145 100 ug
EUR 525.6

CD80 Antibody

DF7682 200ul
EUR 420

CD80 Antibody

1-CSB-PA129040
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against CD80. Recognizes CD80 from Human. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC-p:1:50-300, ELISA:1:10000-20000

CD80 Antibody

1-CSB-PA130815
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD80. Recognizes CD80 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100

CD80 Antibody

1-CSB-PA004959GA01HU
  • EUR 716.40
  • EUR 399.60
  • 150ul
  • 50ul
Description: A polyclonal antibody against CD80. Recognizes CD80 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB

CD80 Antibody

1-CSB-PA277650
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD80. Recognizes CD80 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200

CD80 Antibody

F48980-0.08ML 0.08 ml
EUR 140.25
Description: CD80, or activation antigen B7-1 (formerly referred to as B7) provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells.

CD80 Antibody

F48980-0.4ML 0.4 ml
EUR 322.15
Description: CD80, or activation antigen B7-1 (formerly referred to as B7) provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells.

CD80 antibody

PAab09813 100 ug
EUR 463.2

CD80 Antibody

RQ4248 100 ug
EUR 356.15
Description: Cluster of Differentiation 80 (also CD80 and B7-1) is a protein found on activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells. The CD80 genes encode B7-1 which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types.

CD80 Antibody

R34234-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: B-lymphocyte activation antigen B7, LAB7

CD80 Antibody

R30433 100 ug
EUR 356.15
Description: Cluster of Differentiation 80(also CD80 and B7-1) is a protein found on activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28(for autoregulation and intercellular association) and CTLA-4(for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells. The CD80 genes encode B7-1 which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types. Reeves et al.(1997) stated that B7-1 and B7-2 provide a costimulatory signal to T cells by interacting with CD28 and CTLA4.

CD80 Antibody

R30434 100 ug
EUR 356.15
Description: Cluster of Differentiation 80(also CD80 and B7-1) is a protein found on activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28(for autoregulation and intercellular association) and CTLA-4(for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells. The CD80 genes encode B7-1 which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types. Reeves et al.(1997) stated that B7-1 and B7-2 provide a costimulatory signal to T cells by interacting with CD28 and CTLA4.

CD80 Antibody

RQ6838 100ug
EUR 356.15
Description: Cluster of Differentiation 80 (also CD80 and B7-1) is a protein found on activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells. The CD80 genes encode B7-1 which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types.

CD80 Antibody

V3297-100UG 100 ug
EUR 349.3
Description: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

CD80 Antibody

V3297-20UG 20 ug
EUR 153.3
Description: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

CD80 Antibody

V3297SAF-100UG 100 ug
EUR 349.3
Description: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

CD80 Antibody

V7382-100UG 100 ug
EUR 349.3
Description: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

CD80 Antibody

V7382-20UG 20 ug
EUR 153.3
Description: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

CD80 Antibody

V7382IHC-7ML 7 ml
EUR 349.3
Description: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

CD80 Antibody

V7382SAF-100UG 100 ug
EUR 349.3
Description: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

CD80 Antibody

V7498-100UG 100 ug
EUR 349.3
Description: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

CD80 Antibody

V7498-20UG 20 ug
EUR 153.3
Description: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

CD80 Antibody

V7498SAF-100UG 100 ug
EUR 349.3
Description: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

CD80 Antibody

V8234-100UG 100 ug
EUR 349.3
Description: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

CD80 Antibody

V8234-20UG 20 ug
EUR 153.3
Description: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

CD80 Antibody

V8234SAF-100UG 100 ug
EUR 349.3
Description: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

CD80 Antibody

V8522-100UG 100 ug
EUR 349.3
Description: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

CD80 Antibody

V8522-20UG 20 ug
EUR 153.3
Description: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

CD80 Antibody

V8522SAF-100UG 100 ug
EUR 349.3
Description: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

CD80 ORF Vector (Human) (pORF)

ORF017064 1.0 ug DNA
EUR 114

anti-CD80

YF-PA10781 50 ug
EUR 435.6
Description: Mouse polyclonal to CD80

anti-CD80

YF-PA10782 100 ul
EUR 483.6
Description: Rabbit polyclonal to CD80

anti-CD80

YF-PA10784 100 ug
EUR 483.6
Description: Rabbit polyclonal to CD80

T-lymphocyte activation antigen CD80 (CD80) Antibody

20-abx019054
  • EUR 410.40
  • EUR 109.20
  • 100 ug
  • 10 ug

Rat Anti Mouse Cd80 Monoclonal Antibody

CABT-46717RM 0.1 mg
EUR 546

CD80 ELISA Kit (Human) (OKBB01512)

OKBB01512 96 Wells
EUR 684
Description: Description of target: The protein CD80(Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. It is also known as B7-1. The cDNA for B7-1 predicts a type I membrane protein, i.e., one synthesized with a signal peptide that is cleaved upon translocation across the endoplasmic membrane. The protein is predicted to contain 2 extracellular domains structurally similar to those of Ig, a hydrophobic transmembrane region, and a short cytoplasmic domain. The CD80 and CD86 genes encode B7-1 and B7-2, respectively, which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types. B7-1 and B7-2 provide a costimulatory signal to T cells by interacting with CD28 and CTLA4.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <10pg/ml

CD80 ELISA Kit (Human) (OKCD07374)

OKCD07374 96 Wells
EUR 1123.2
Description: Description of target: The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 33pg/mL

CD80

80A-100T 100 test
EUR 450

CD80

80F-100T 100 test
EUR 372

CD80

80PE-100T 100 test
EUR 762

CD80

MO80A(V100) 100 ug
EUR 60

CD80

MO80A(V25) 25 ug
EUR 60

CD80

MO80B(V100) 100 ug
EUR 60

CD80

MO80B(V25) 25 ug
EUR 60

CD80

MO80CFB(V100) 100 ug
EUR 60

CD80

MO80CFB(V25) 25 ug
EUR 60

CD80

MO80F(V100) 100 ug
EUR 60

CD80

MO80F(V25) 25 ug
EUR 60

CD80

MO80F(V500) 500 ug
EUR 60

CD80

MO80PE(V100) 100 ug
EUR 60

CD80

MO80PE(V25) 25 ug
EUR 60

Leave a Reply

Your email address will not be published.